Microwave-assisted synthesis of medium-sized heterocycles

被引：152

作者：

Sharma, Abhishek ^{[1
]}

Appukkuttan, Prasad ^{[1
,2
]}

van der Eycken, Erik ^{[1
]}

机构：

[1] Katholieke Univ Leuven, Dept Chem, LOMAC, B-3001 Louvain, Belgium

[2] S2 Navnit Sphatika, Bangalore 560076, Karnataka, India

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 11期

关键词：

RING-CLOSING METATHESIS; SOLID-PHASE SYNTHESIS; ANTITUBULIN ACTIVITY; EFFICIENT SYNTHESIS; ENHANCED SYNTHESIS; RECEPTOR LIGANDS; LACTONES; ANALOGS; AMARYLLIDACEAE; CYCLIZATION;

D O I：

10.1039/c1cc15238f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The development of new strategies for synthesis of medium-sized heterocycles has remained a highly attractive but challenging proposition. In the last few years, the application of microwave irradiation has greatly facilitated the construction of such heterocyclic ring systems through a myriad of different synthetic approaches. This feature article illustrates the progress made in the microwave-assisted synthesis of medium-sized heterocycles with an emphasis on examples describing the use of a dedicated microwave synthesizer.

引用

页码：1623 / 1637

页数：15

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