Pivotal MicroRNAs in Melanoma: A Mini-Review

被引：7
|
作者：
Deng, Zhenjun [1 ]
Hao, Jingang [2 ]
Lei, Dongyun [1 ]
He, Yongjing [3 ]
Lu, Lechun [1 ,4 ]
He, Li [1 ]
机构：
[1] Kunming Med Univ, Dept Dermatol, Affiliated Hosp 1, 295 Xichang Rd, Kunming 650032, Yunnan, Peoples R China
[2] Kunming Med Univ, Affiliated Hosp 2, Dept Med Image, Kunming, Yunnan, Peoples R China
[3] Kunming Med Univ, Affiliated Hosp 2, Dept Plast Surg, Kunming, Yunnan, Peoples R China
[4] Kunming Med Univ, Dept Physiol, Kunming 650032, Yunnan, Peoples R China
来源：
MOLECULAR DIAGNOSIS & THERAPY | 2016年 / 20卷 / 05期
基金：
中国国家自然科学基金;
关键词：
TUMOR-SUPPRESSOR; CUTANEOUS MELANOMA; MALIGNANT-MELANOMA; MESENCHYMAL TRANSITION; CELL PROLIFERATION; ALTERED EXPRESSION; DOWN-REGULATION; CANCER; INVASION; METASTASIS;
D O I：
10.1007/s40291-016-0219-y
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Melanoma is a common skin cancer associated with ultraviolet light exposure and genetic variance. However, the etiology and molecular mechanisms of melanoma remain unknown. Recent studies have shown that microRNAs (miRNAs) can play key roles in the development and prognosis of this disease. In this study, we reviewed several pivotal miRNAs that may contribute to melanoma by involvement in the processes of invasion, migration, and metastasis of melanoma cells.
引用
收藏
页码：449 / 455
页数：7
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