A new α-pyrone metabolite from a mangrove plant endophytic fungus, Fusarium sp.

被引:13
|
作者
Shiono, Yoshihito [1 ]
Shibuya, Fumiaki [1 ]
Koseki, Takuya [1 ]
Harizon [2 ]
Supratman, Unang [2 ]
Uesugi, Shota [3 ]
Kimura, Ken-ichi [3 ]
机构
[1] Yamagata Univ, Dept Bioresource Engn, Fac Agr, Tsuruoka, Yamagata 9978555, Japan
[2] Padjadjaran State Univ, Fac Math & Nat Sci, Dept Chem, Sumedang 45363, Indonesia
[3] Iwate Univ, United Grad Sch Agr Sci, Biol Chem Lab, Morioka, Iwate 0208550, Japan
关键词
mangrove; Fusarium sp; Ca2+-signaling; cladobotrin V; endophyte; CALCINEURIN;
D O I
10.1080/10286020.2014.961919
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
A new alpha-pyrone derivative, compound 2, and a known one, cladobotrin V, were isolated from the culture broth of the mangrove endophyte Fusarium sp. IM-37. Their structures were determined spectroscopically and compared with previously reported spectral data. Compound 2 restored the growth inhibition caused by hyperactivated Ca2+-signaling in mutant yeast.
引用
收藏
页码:403 / 408
页数:6
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