Human dendritic cell subsets: An updated view of their ontogeny and functional specialization

被引：31
|
作者：
Segura, Elodie [1 ]
机构：
[1] PSL Res Univ, Inst Curie, Paris, France
来源：
EUROPEAN JOURNAL OF IMMUNOLOGY | 2022年 / 52卷 / 11期
关键词：
Human; dendritic cell; subsets; ANTIGEN CROSS-PRESENTATION; T-CELLS; DISTINCT SUBSETS; INFECTED CELLS; HUMAN CD1C(+); FACTOR E2-2; DIFFERENTIATION; MONOCYTES; VIRUS; HETEROGENEITY;
D O I：
10.1002/eji.202149632
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Human DCs have been divided into several subsets based on their phenotype and ontogeny. Recent high throughput single-cell methods have revealed additional heterogeneity within human DC subsets, and new subpopulations have been proposed. In this review, we provide an updated view of the human DC subsets and of their ontogeny supported by recent clinical studies . We also summarize their main characteristics including their functional specialization.
引用
收藏
页码：1759 / 1767
页数：9
相关论文
共 50 条
  • [41] Contrariety of Human Bone Marrow Mesenchymal Stromal Cell Functionality in Modulating Circulatory Myeloid and Plasmacytoid Dendritic Cell Subsets
    Uwazie, Crystal C. C.
    Faircloth, Tyler U. U.
    Parr, Rhett N. N.
    Reddy, Yenamala U. U.
    Hematti, Peiman
    Rajan, Devi
    Chinnadurai, Raghavan
    BIOLOGY-BASEL, 2023, 12 (05):
  • [42] Impact of Varicella-Zoster Virus on Dendritic Cell Subsets in Human Skin during Natural Infection
    Huch, Jennifer H.
    Cunningham, Anthony L.
    Arvin, Ann M.
    Nasr, Najla
    Santegoets, Saskia J. A. M.
    Slobedman, Eric
    Slobedman, Barry
    Abendroth, Allison
    JOURNAL OF VIROLOGY, 2010, 84 (08) : 4060 - 4072
  • [43] Influenza vaccines differentially regulate the interferon response in human dendritic cell subsets
    Athale, Shruti
    Banchereau, Romain
    Thompson-Snipes, Luann
    Wang, Yuanyuan
    Palucka, Karolina
    Pascual, Virginia
    Banchereau, Jacques
    SCIENCE TRANSLATIONAL MEDICINE, 2017, 9 (382)
  • [44] Profiling dendritic cell subsets in the patients with active pulmonary tuberculosis
    Lu, Yuan-Bin
    Xiao, De-Qian
    Liang, Kui-Di
    Zhang, Jun-Ai
    Wang, Wan-Dang
    Yu, Shi-Yan
    Zheng, Bi-Ying
    Gao, Yu-Chi
    Dai, You-Chao
    Jia, Yan
    Chen, Chen
    Zhuang, Ze-Gang
    Wang, Xin
    Fu, Xiao-Xia
    Zhou, Yong
    Zhong, Jixin
    Chen, Zheng W.
    Xu, Jun-Fa
    MOLECULAR IMMUNOLOGY, 2017, 91 : 86 - 96
  • [45] CD56 marks human dendritic cell subsets with cytotoxic potential
    Roothans, Dessie
    Smits, Evelien
    Lion, Eva
    Tel, Jurjen
    Anguille, Sebastien
    ONCOIMMUNOLOGY, 2013, 2 (02):
  • [46] Immunophenotypical, morphologic, and functional characterization of maturation-associated plasmacytoid dendritic cell subsets in normal adult human bone marrow
    Martin-Martin, Lourdes
    Almeida, Julia
    Maria Hernandez-Campo, Pilar
    Luz Sanchez, Maria
    Lecrevisse, Quentin
    Orfao, Alberto
    TRANSFUSION, 2009, 49 (08) : 1692 - 1708
  • [47] Presence of Dendritic Cell Subsets in Sentinel Nodes of Breast Cancer Patients Is Related to Nodal Burden
    Szpor, Joanna
    Streb, Joanna
    Glajcar, Anna
    Sadowski, Piotr
    Streb-Smolen, Anna
    Jach, Robert
    Hodorowicz-Zaniewska, Diana
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (15)
  • [48] Human lymphoid organ dendritic cell identity is predominantly dictated by ontogeny, not tissue microenvironment
    Heidkamp, Gordon F.
    Sander, Jil
    Lehmann, Christian H. K.
    Heger, Lukas
    Eissing, Nathalie
    Baranska, Anna
    Luehr, Jennifer J.
    Hoffmann, Alana
    Reimer, Katharina C.
    Lux, Anja
    Soeder, Stephan
    Hartmann, Arndt
    Zenk, Johannes
    Ulas, Thomas
    McGovern, Naomi
    Alexiou, Christoph
    Spriewald, Bernd
    Mackensen, Andreas
    Schuler, Gerold
    Schauf, Burkhard
    Forster, Anja
    Repp, Roland
    Fasching, Peter A.
    Purbojo, Ariawan
    Cesnjevar, Robert
    Ullrich, Evelyn
    Ginhoux, Florent
    Schlitzer, Andreas
    Nimmerjahn, Falk
    Schultze, Joachim L.
    Dudziak, Diana
    SCIENCE IMMUNOLOGY, 2016, 1 (06)
  • [49] Development of murine plasmacytoid dendritic cell subsets
    Naik, SH
    Corcoran, LM
    Wu, L
    IMMUNOLOGY AND CELL BIOLOGY, 2005, 83 (05) : 563 - 570
  • [50] Dendritic cell subsets and immune regulation in the lung
    de Heer, HJ
    Hammad, H
    Kool, MA
    Lambrecht, BN
    SEMINARS IN IMMUNOLOGY, 2005, 17 (04) : 295 - 303
12345