Ponatinib given for advanced leukemia relapse after allo-SCT

被引:14
作者
Hirschbuehl, K. [1 ]
Rank, A. [1 ]
Pfeiffer, T. [1 ]
Slawik, H. R.
Schlimok, G. [1 ]
Kolb, H. J. [2 ]
Schmid, C. H. [1 ]
机构
[1] Klinikum Augsburg, Dept Hematol & Oncol, Augsburg, Germany
[2] Univ Munich, Klinikum Rechts Isar, Dept Hematol & Oncol, Munich, Germany
关键词
CHROMOSOME-POSITIVE LEUKEMIAS; CHRONIC MYELOGENOUS LEUKEMIA; STEM-CELL TRANSPLANTATION; ALLOGENEIC TRANSPLANTATION; IMATINIB-MESYLATE;
D O I
10.1038/bmt.2014.301
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
引用
收藏
页码:599 / 600
页数:2
相关论文
共 9 条
  • [1] A Phase 2 Trial of Ponatinib in Philadelphia Chromosome-Positive Leukemias
    Cortes, J. E.
    Kim, D. -W.
    Pinilla-Ibarz, J.
    le Coutre, P.
    Paquette, R.
    Chuah, C.
    Nicolini, F. E.
    Apperley, J. F.
    Khoury, H. J.
    Talpaz, M.
    DiPersio, J.
    DeAngelo, D. J.
    Abruzzese, E.
    Rea, D.
    Baccarani, M.
    Mueller, M. C.
    Gambacorti-Passerini, C.
    Wong, S.
    Lustgarten, S.
    Rivera, V. M.
    Clackson, T.
    Turner, C. D.
    Haluska, F. G.
    Guilhot, F.
    Deininger, M. W.
    Hochhaus, A.
    Hughes, T.
    Goldman, J. M.
    Shah, N. P.
    Kantarjian, H.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2013, 369 (19) : 1783 - 1796
  • [2] Ponatinib in Refractory Philadelphia Chromosome-Positive Leukemias
    Cortes, Jorge E.
    Kantarjian, Hagop
    Shah, Neil P.
    Bixby, Dale
    Mauro, Michael J.
    Flinn, Ian
    O'Hare, Thomas
    Hu, Simin
    Narasimhan, Narayana I.
    Rivera, Victor M.
    Clackson, Tim
    Turner, Christopher D.
    Haluska, Frank G.
    Druker, Brian J.
    Deininger, Michael W. N.
    Talpaz, Moshe
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2012, 367 (22) : 2075 - 2088
  • [3] Standardized definitions of molecular response in chronic myeloid leukemia
    Cross, N. C. P.
    White, H. E.
    Mueller, M. C.
    Saglio, G.
    Hochhaus, A.
    [J]. LEUKEMIA, 2012, 26 (10) : 2172 - 2175
  • [4] Proceedings from the National Cancer Institute's Second International Workshop on the Biology, Prevention, and Treatment of Relapse after Hematopoietic Stem Cell Transplantation: Part III. Prevention and Treatment of Relapse after Allogeneic Transplantation
    de Lima, Marcos
    Porter, David L.
    Battiwalla, Minoo
    Bishop, Michael R.
    Giralt, Sergio A.
    Hardy, Nancy M.
    Kroeger, Nicolaus
    Wayne, Alan S.
    Schmid, Christoph
    [J]. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2014, 20 (01) : 4 - 13
  • [5] Extended follow-up of patients treated with imatinib mesylate (Gleevec) for chronic myelogenous leukemia relapse after allogeneic transplantation:: Durable cytogenetic remission and conversion to complete donor chimerism without graft-versus-host disease
    Deangelo, DJ
    Hochberg, EP
    Alyea, EP
    Longtine, J
    Lee, S
    Galinsky, I
    Parekkedon, B
    Ritz, J
    Antin, JH
    Stone, RM
    Soiffer, RJ
    [J]. CLINICAL CANCER RESEARCH, 2004, 10 (15) : 5065 - 5071
  • [6] Sustained complete molecular remissions after treatment with imatinib-mesylate in patients with failure after allogeneic stem cell transplantation for chronic myelogenous leukemia:: Results of a prospective phase II open-label multicenter study
    Hess, G
    Bunjes, D
    Siegert, W
    Schwerdtfeger, R
    Ledderose, G
    Wassmann, B
    Kobbe, G
    Bornhäuser, M
    Hochhaus, A
    Ullmann, AJ
    Kindler, T
    Hans, U
    Gschaidmeier, H
    Huber, C
    Fischer, T
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (30) : 7583 - 7593
  • [7] Clinical impact of dose modification and dose intensity on response to ponatinib (PON) in patients (pts) with Philadelphia chromosome-positive (Ph plus ) leukemias.
    Hochhaus, Andreas
    Pinilla-Ibarz, Javier
    Kim, Dong-Wook
    Le Coutre, Philipp D.
    Paquette, Ronald
    Chuah, Charles
    Nicolini, Franck E.
    Apperley, Jane
    Khoury, Hanna Jean
    Baccarani, Michele
    Lustgarten, Stephanie
    Rivera, Victor M.
    Haluska, Frank G.
    Guilhot, Francois
    Deininger, Michael W. N.
    Hughes, Timothy P.
    Shah, Neil P.
    Kantarjian, Hagop M.
    Talpaz, Moshe
    Cortes, Jorge E.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (15)
  • [8] Current Status and Perspectives of Tyrosine Kinase Inhibitor Treatment in the Posttransplant Period in Patients with Chronic Myelogenous Leukemia (CML)
    Klyuchnikov, Evgeny
    Kroeger, Nicolaus
    Brummendorf, Tim H.
    Wiedemann, Bettina
    Zander, Axel Rolf
    Bacher, Ulrike
    [J]. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2010, 16 (03) : 301 - 310
  • [9] Ponatinib in Philadelphia Chromosome-Positive Leukemias
    Quintas-Cardama, Alfonso
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2014, 370 (06) : 577 - 577