Characterizing Concomitant Follicular Lymphoma and Gastric Carcinoma Using 68Ga-FAPI-04 and 18F-FDG PET/CT

被引:5
作者
Chen, Xuetao [1 ]
Wei, Maomao [1 ]
Wang, Shuailiang [1 ]
Yang, Zhi [1 ]
Wang, Xuejuan [1 ]
机构
[1] Peking Univ Canc Hosp & Inst, Dept Nucl Med, Key Lab Carcinogenesis & Translat Res,Minist Educ, Key Lab Res & Evaluat Radiopharmaceut,Natl Med Pr, 52 Fucheng Rd, Beijing 100142, Peoples R China
基金
中国国家自然科学基金;
关键词
Ga-68-FAPI-04; PET/CT; gastric adenocarcinoma; follicular lymphoma; FDG PET/CT;
D O I
10.1097/RLU.0000000000003781
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
ABSTRACT: We herein report a case involving a 67-year-old man with concomitant progressive follicular lymphoma and gastric carcinoma. Baseline 18F-FDG PET/CT showed high metabolic activity in multiple nodal stations and a thickened gastric antrum wall, whereas 68Ga-FAPI-04 PET/CT depicted very intense tracer uptake in the gastric lesion but mild uptake in the nodes. After the treatment, complete remission from lymphadenopathy was achieved, whereas the gastric lesion accumulated more radiotracers compared with baseline levels. Despite our incorrect initial assumption of B-cell transformation, molecular imaging was able to profile the characteristics of these 2 diseases. Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.
引用
收藏
页码:81 / 82
页数:2
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  • [1] Comparison of [68Ga]Ga-DOTA-FAPI-04 and [18F] FDG PET/CT for the diagnosis of primary and metastatic lesions in patients with various types of cancer
    Chen, Haojun
    Pang, Yizhen
    Wu, Jingxun
    Zhao, Liang
    Hao, Bing
    Wu, Jing
    Wei, Jihong
    Wu, Siming
    Zhao, Long
    Luo, Zuoming
    Lin, Xuehua
    Xie, Chengrong
    Sun, Long
    Lin, Qin
    Wu, Hua
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2020, 47 (08) : 1820 - 1832
  • [2] 68Ga-FAPI PET/CT: Tracer Uptake in 28 Different Kinds of Cancer
    Kratochwil, Clemens
    Flechsig, Paul
    Lindner, Thomas
    Abderrahim, Labidi
    Altmann, Annette
    Mier, Walter
    Adeberg, Sebastian
    Rathke, Hendrik
    Roehrich, Manuel
    Winter, Hauke
    Plinkert, Peter K.
    Marme, Frederik
    Lang, Matthias
    Kauczor, Hans-Ulrich
    Jaeger, Dirk
    Debus, Juergen
    Haberkorn, Uwe
    Giesel, Frederik L.
    [J]. JOURNAL OF NUCLEAR MEDICINE, 2019, 60 (06) : 801 - 805
  • [3] Unsuspected Synchronous Thyroid Carcinoma Revealed on a Post-Therapy F-18 FDG PET/CT, in a Patient With Follicular Lymphoma
    Makis, William
    Hickeson, Marc
    Novales-Diaz, Javier-A
    [J]. CLINICAL NUCLEAR MEDICINE, 2010, 35 (11) : 879 - 881
  • [4] Radiation Dosimetry and Biodistribution of 68Ga-FAPI-46 PET Imaging in Cancer Patients
    Meyer, Catherine
    Dahlbom, Magnus
    Lindner, Thomas
    Vauclin, Sebastien
    Mona, Christine
    Slavik, Roger
    Czernin, Johannes
    Haberkorn, Uwe
    Calais, Jeremie
    [J]. JOURNAL OF NUCLEAR MEDICINE, 2020, 61 (08) : 1171 - 1177
  • [5] Comparison of 68Ga-FAPI and 18F-FDG Uptake in Gastric, Duodenal, and Colorectal Cancers
    Pang, Yizhen
    Zhao, Liang
    Luo, Zuoming
    Hao, Bing
    Wu, Hua
    Lin, Qin
    Sun, Long
    Chen, Haojun
    [J]. RADIOLOGY, 2021, 298 (02) : 393 - 402
  • [6] Synchronous Second Primary Neoplasms Detected by Initial Staging F-18 FDG PET/CT Examination in Patients With Non-Hodgkin Lymphoma
    Papajik, Tomas
    Myslivecek, Miroslav
    Sedova, Zuzana
    Buriankova, Eva
    Prochazka, Vit
    Raida, Ludek
    Kubova, Zuzana
    Neoral, Cestmir
    Starostka, David
    Mikula, Petr
    Melichar, Bohuslav
    Kucerova, Ladislava
    Tichy, Martin
    Indrak, Karel
    [J]. CLINICAL NUCLEAR MEDICINE, 2011, 36 (07) : 509 - 512
  • [7] 68Ga-NOTA-FAPI-04 PET/CT in a patient with primary gastric diffuse large B cell lymphoma: comparisons with [18F] FDG PET/CT
    Wang, Guochang
    Jin, Xiao
    Zhu, Hua
    Wang, Shuailiang
    Ding, Jin
    Zhang, Yan
    Yang, Zhi
    Wang, Xuejuan
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2021, 48 (02) : 647 - 648
  • [8] Unsuspected synchronous lung cancer unveiled on FDG PET after chemotherapy for non-Hodgkin lymphoma
    Zhang, Yifan
    Li, Geming
    Zhuang, Hongming
    [J]. CLINICAL NUCLEAR MEDICINE, 2008, 33 (02) : 109 - 110