Carijodienone from the Octocoral Carijoa multiflora. A Spiropregnane-Based Steroid

被引：48

作者：

Diaz-Marrero, Ana R. ^{[1
]}

Porras, Gina ^{[1
]}

Aragon, Zulma ^{[1
]}

de la Rosa, Jose M. ^{[1
]}

Dorta, Enrique ^{[1
]}

Cueto, Mercedes ^{[1
]}

D'Croz, Luis ^{[2
]}

Mate, Juan ^{[3
]}

Darias, Jose ^{[1
]}

机构：

[1] CSIC, Inst Prod Nat & Agrobiol, Tenerife 38206, Spain

[2] Univ Panama, Dept Biol Marina & Limnol, Panama City, Panama

[3] Smithsonian Trop Res Inst, Balboa, Panama

来源：

JOURNAL OF NATURAL PRODUCTS | 2011年 / 74卷 / 02期

关键词：

T76 SCENEDESMUS QUADRICAUDA; SOFT CORAL; TELESTO-RIISEI; ELYSIAPYRONES; BIOSYNTHESIS; PUNAGLANDINS; PREGNANES; CULTURES; CHAIN;

D O I：

10.1021/np1007608

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new steroids (1 and 2) and the known pregna-1,4,20-trien-3-one (3) have been isolated from the Pacific octocoral Carijoa multiflora. Compound 1 possesses a novel spiropregnane-based steroidal skeleton. The photochemical transformation of 3 into 1. allowed the assignment of the absolute configuration at C-10 of 1. The antibacterial activities of compounds 1 and 3 were evaluated against a panel of bacterial strains.

引用

页码：292 / 295

页数：4

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