General measures of cognition

被引:56
作者
Ferris, SH [1 ]
机构
[1] NYU, Sch Med, Silberstein Inst Aging & Dementia, New York, NY 10016 USA
关键词
vascular dementia; cognitive assessment; clinical trials;
D O I
10.1017/S1041610203009220
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
A general cognitive performance battery is needed as a primary outcome in vascular dementia clinical trials. Because there is considerable overlap between vascular dementia and Alzheimer's disease (AD) in the pattern of cognitive impairment, a reasonable approach to developing an optimal vascular dementia battery is to begin with a widely used AD measure and improve its sensitivity to the cognitive domains that are more prominent in vascular dementia. Thus the VaDAS-cog has evolved, which comprises the ADAS-cog with additional frontal lobe subtests covering attention, working memory, executive function, and verbal fluency. Validation of this new cognitive instrument will be supported by its successful use in vascular dementia clinical trials.
引用
收藏
页码:215 / 217
页数:3
相关论文
共 4 条
  • [1] Ferrando SJ, 1999, PSYCHOSOMATICS, V40, P142
  • [2] Ferris SH, 1997, ALZ DIS ASSOC DIS, V11, P34
  • [3] Gauthier S, 2001, INT J CLIN PRACT, P29
  • [4] Mohs RC, 1997, ALZ DIS ASSOC DIS, V11, pS13