Synthesis of Some Symmetrical Novel Bis-thiosemicarbazides, 1,2,4-Triazoles, 1,3,4-Thiadiazoles, and Their Derivatives

被引:9
|
作者
Mobinikhaledi, A. [1 ]
Foroughifar, N. [1 ]
Kalhor, M. [1 ]
Ebrahimi, S. [1 ]
Fard, M. A. Bodaghi [1 ]
机构
[1] Arak Univ, Dept Chem, Arak 38156879, Iran
关键词
Thiadiazole; thiosemicarbazide; triazole; THIADIAZOLES; AGENTS;
D O I
10.1080/10426507.2010.480949
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Synthesis of some novel bis-1,2,4-triazoles 5a-c and 1,3,4-thiadiazoles 6a-c bearing a pyridyl unit using 4-(1,4-phenylene)bis-1-(x-picolinoyl)-thiosemicarbazide (x = 2,3,4) in an acidic and alkaline solution, respectively, is reported. The S-alkylation of symmetrical triazole derivatives 7a-c and 8a-c is also reported. The structures of the synthesized compounds result from the IR and NMR spectroscopic data. GRAPHICAL ABSTRACT[image omitted].
引用
收藏
页码:67 / 73
页数:7
相关论文
共 50 条
  • [21] Synthesis and characterization of novel fluorinated thiazolyl 1,3,4-thiadiazoles, 1,2,4-triazoles.and 1,3-thiazoles by conventional and non-conventional methods
    Akolkar, H. N.
    Karale, B. K.
    Randhavane, P. V.
    Dalavi, N. R.
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2017, 56 (03): : 348 - 355
  • [22] SYNTHESIS OF SOME N-ALKYLATED 1,2,4-TRIAZOLES, 1,3,4-OXADIAZOLES, AND 1,3,4-THIADIAZOLES BASED ON N-(FURAN-2-YL-METHYLIDENE)-4,6-DIMETHYL-1H-PYRAZOLO-[3,4-b]PYRIDINE-3-AMINE
    El-Essawy, F. A.
    Rady, S. I. M.
    CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2011, 47 (04) : 497 - 506
  • [23] Synthesis and analgesic activity of new 1,3,4-oxadiazoles and 1,2,4-triazoles
    Almasirad, Ali
    Shafiee, Abbas
    Abdollahi, Mohammad
    Noeparast, Amir
    Shahrokhinejad, Nasir
    Vousooghi, Nasim
    Tabatabai, Sayyed Abbas
    Khorasani, Reza
    MEDICINAL CHEMISTRY RESEARCH, 2011, 20 (04) : 435 - 442
  • [24] A novel route to 1,2,4-triazoles
    Kidwai, M
    Misra, P
    Bhushan, KR
    Dave, B
    SYNTHETIC COMMUNICATIONS, 2000, 30 (16) : 3031 - 3040
  • [25] Synthesis and Biological Activities of Derivatives of 3,6-Diphenoxymethyl-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles
    Sun Xiao-Hong
    Bai Yan
    Liu Yuan-Fa
    Chen Bang
    Jia Ying-Qi
    CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2011, 32 (06): : 1312 - 1317
  • [26] Synthesis of new pyrimidinylthio-substituted 1,3,4-oxa(thia)diazoles and 1,2,4-triazoles
    Burbuliene, Milda M.
    Simkus, Aliona
    Vainilavicius, Povilas
    JOURNAL OF SULFUR CHEMISTRY, 2012, 33 (04) : 403 - 411
  • [27] Synthesis, biological activities, molecular docking, theoretical calculations of some 1,3,4-oxadiazoles, 1,2,4-triazoles, and 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines derivatives
    Tolan, Hala E. M.
    Fahim, Asmaa M.
    Ismael, Eman H. I.
    JOURNAL OF MOLECULAR STRUCTURE, 2023, 1283
  • [28] Synthesis of some substituted 1,2,4-triazole and 1,3,4-thiadiazole derivatives
    Dilanyan, E. R.
    Hovsepyan, T. R.
    Melik-Ohanjanyan, R. G.
    CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2008, 44 (11) : 1395 - 1397
  • [29] Synthesis and Biological Evaluation of 1,2,4-Triazoles and 1,3,4-Oxadiazoles Derivatives Linked to 1,4-Dihydropyridines Scaffold
    Ziaie, Maghsoud
    Dilmaghani, Karim Akbari
    Tukmechi, Amir
    ACTA CHIMICA SLOVENICA, 2017, 64 (04) : 895 - 901
  • [30] Azodicarboxylates: valuable reagents for the multicomponent synthesis of novel 1,3,4-thiadiazoles and imidazo[2,1-b][1,3,4] thiadiazoles
    Zarganes-Tzitzikas, Tryfon
    Neochoritis, Constantinos G.
    Stephanidou-Stephanatou, Julia
    Tsoleridis, Constantinos A.
    Buth, Gernot
    Kostakis, George E.
    TETRAHEDRON, 2013, 69 (24) : 5008 - 5015