Synthesis of Some Symmetrical Novel Bis-thiosemicarbazides, 1,2,4-Triazoles, 1,3,4-Thiadiazoles, and Their Derivatives

被引：9
|
作者：
Mobinikhaledi, A. [1 ]
Foroughifar, N. [1 ]
Kalhor, M. [1 ]
Ebrahimi, S. [1 ]
Fard, M. A. Bodaghi [1 ]
机构：
[1] Arak Univ, Dept Chem, Arak 38156879, Iran
来源：
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2011年 / 186卷 / 01期
关键词：
Thiadiazole; thiosemicarbazide; triazole; THIADIAZOLES; AGENTS;
D O I：
10.1080/10426507.2010.480949
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Synthesis of some novel bis-1,2,4-triazoles 5a-c and 1,3,4-thiadiazoles 6a-c bearing a pyridyl unit using 4-(1,4-phenylene)bis-1-(x-picolinoyl)-thiosemicarbazide (x = 2,3,4) in an acidic and alkaline solution, respectively, is reported. The S-alkylation of symmetrical triazole derivatives 7a-c and 8a-c is also reported. The structures of the synthesized compounds result from the IR and NMR spectroscopic data. GRAPHICAL ABSTRACT[image omitted].
引用
收藏
页码：67 / 73
页数：7
相关论文
共 50 条
  • [1] Synthesis of substituted 1,2,4-triazoles and 1,3,4-thiadiazoles
    Hovsepian T.R.
    Dilanian E.R.
    Engoyan A.P.
    Melik-Ohanjanian R.G.
    Chemistry of Heterocyclic Compounds, 2004, 40 (09) : 1194 - 1198
  • [2] Efficient synthesis of some novel symmetrical and unsymmetrical pyridine bis-1,2,4-triazoles and bis-1,3,4-thiadiazoles
    Foroughifar, Naser
    Mobinikhaledi, Akbar
    Rafiee, Abdolhossein
    JOURNAL OF CHEMICAL RESEARCH, 2014, (02) : 111 - 114
  • [3] Synthesis and QSAR studies of thiosemicarbazides, 1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles derivatives as potential antibacterial agents
    Desai, N. C.
    Bhavsar, A. M.
    Shah, M. D.
    Saxena, Anil K.
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2008, 47 (04): : 579 - 585
  • [4] Synthesis and Antitumor Properties of New 1,2,4-Triazoles and 1,3,4-Thiadiazoles
    Ovsepyan, T. R.
    Arsenyan, F. G.
    Nersesyan, L. E.
    Danielyan, I. S.
    Agaronyan, A. G.
    Melik-Ogandzhanyan, R. G.
    PHARMACEUTICAL CHEMISTRY JOURNAL, 2017, 50 (11) : 724 - 727
  • [5] Synthesis and Antitumor Properties of New 1,2,4-Triazoles and 1,3,4-Thiadiazoles
    T. R. Ovsepyan
    F. G. Arsenyan
    L. E. Nersesyan
    I. S. Danielyan
    A. G. Agaronyan
    R. G. Melik-Ogandzhanyan
    Pharmaceutical Chemistry Journal, 2017, 50 : 724 - 727
  • [6] SYNTHESIS AND ANTIMICROBIAL EVALUATION OF NOVEL PYRIDINE ANCHORED THIAZOLYL 1,3,4-THIADIAZOLES AND 1,2,4-TRIAZOLES
    Akolkar, H. N.
    Darekar, N. R.
    Kundlikar, S. G.
    Karale, B. K.
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2015, 25 (01) : 87 - 90
  • [7] Synthesis and bioassay of a new class of disubstituted 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles
    Sekhar, Mangali Madhu
    Yamini, Gudi
    Divya, Kuppi Reddy Gari
    Padmavathi, Venkatapuram
    Padmaja, Adivireddy
    MEDICINAL CHEMISTRY RESEARCH, 2019, 28 (07) : 1049 - 1062
  • [8] Synthesis and bioassay of a new class of disubstituted 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles
    Mangali Madhu Sekhar
    Gudi Yamini
    Kuppi Reddy Gari Divya
    Venkatapuram Padmavathi
    Adivireddy Padmaja
    Medicinal Chemistry Research, 2019, 28 : 1049 - 1062
  • [9] Synthesis and Antimicrobial Activity of Pyrrolyl/Pyrazolyl Arylaminosulfonylmethyl 1,3,4-Oxadiazoles, 1,3,4-Thiadiazoles and 1,2,4-Triazoles
    Padmaja, Adivireddy
    Muralikrishna, Akkarapalli
    Rajasekhar, Chittoor
    Padmavathi, Venkatapuram
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2011, 59 (12) : 1509 - 1517
  • [10] Synthesis and Antimicrobial Activity of New Derivatives of 1,3,4-Thiadiazoles and 1,2,4-Triazoles with 5-Nitroindazole as Support
    Cheptea, Corina
    Sunel, Valeriu
    Desbrieres, Jacques
    Popa, Marcel
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2013, 50 (02) : 366 - 372
12345