Performance of commercial latex agglutination tests for the differentiation of Candida dubliniensis and Candida albicans in routine diagnostics

被引:13
作者
Chryssanthou, E.
Fernandez, V.
Petrini, B.
机构
[1] Karolinska Univ Lab, Dept Clin Microbiol, Solna, Sweden
[2] Swedish Inst Infect Dis Control, Stockholm, Sweden
关键词
Candida dubliniensis; latex agglutination; monoclonal antibodies;
D O I
10.1111/j.1600-0643.2007.00801.x
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Candida dubliniensis is phenotypically similar to Candida albicans and may therefore be underdiagnosed in the clinical microbiology laboratory. The performance of Bichro-Dubli latex agglutination test for rapid species identification of C. dubliniensis was prospectively evaluated on I I I vaginal and 118 respiratory isolates. These had presumptively been identified as C. albicans/C dubliniensis by their green colonies on CHROMagar Candida plates. Bichro-Dubli test identifed 2 (1.8%) vaginal and 6 (5.1%) respiratory isolates as C dubliniensis. The test was also positive for 37 C dubliniensis control strains characterised by 18S-28S DNA-sequencing. Bichro-Dubli test is thus a sensitive and accurate tool for rapid diagnostics in routine laboratories.
引用
收藏
页码:1281 / 1284
页数:4
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