Computational biology - Protein predictions

被引：8

作者：

Dodson, Eleanor J. ^{[1
]}

机构：

[1] Univ York, Dept Chem, York Struct Biol Lab, York YO10 5YW, N Yorkshire, England

来源：

NATURE | 2007年 / 450卷 / 7167期

关键词：

D O I：

10.1038/nature05990

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Predicting the three-dimensional structure of a protein from its amino-acid sequence is a dauntingly complex task. But with colossal computer power and knowledge of other structures, it can be done.

引用

页码：176 / 177

页数：2

共 5 条

[1]

DAS R, 2007, PROTEINS

[2] Likelihood-enhanced fast translation functions [J].

McCoy, AJ ;

Grosse-Kunstleve, RW ;

Storoni, LC ;

Read, RJ .

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2005, 61 :458-464

[3] Rigorous performance evaluation in protein structure modelling and implications for computational biology [J].

Moult, J .

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2006, 361 (1467) :453-458

[4] High-resolution structure prediction and the crystallographic phase problem [J].

Qian, Bin ;

Raman, Srivatsan ;

Das, Rhiju ;

Bradley, Philip ;

McCoy, Airlie J. ;

Read, Randy J. ;

Baker, David .

NATURE, 2007, 450 (7167) :259-264

[5] REDUCTIVE CLEAVAGE OF DISULFIDE BRIDGES IN RIBONUCLEASE [J].

SELA, M ;

WHITE, FH ;

ANFINSEN, CB .

SCIENCE, 1957, 125 (3250) :691-692

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