value;
value-based;
systemic therapy;
cancer;
financial toxicity;
cost of care;
ONCOLOGY VALUE FRAMEWORK;
AMERICAN SOCIETY;
ANTICANCER DRUGS;
CLINICAL BENEFIT;
CANCER;
PEMBROLIZUMAB;
MAGNITUDE;
D O I:
10.3390/curroncol29080456
中图分类号:
R73 [肿瘤学];
学科分类号:
100214 ;
摘要:
The rising cost of cancer care has shed light on an important aspect of healthcare delivery. Financial toxicity of therapy must be considered in clinical practice and policy-making. One way to mitigate the impact of financial toxicity of cancer care is by focusing on an approach of healthcare delivery that aims to deliver value to the patient. Should value of therapy be one of the most important determinants of cancer care? If so, how do we measure it? How can we implement it in routine clinical practice? In this viewpoint, we discuss value-based care in systemic therapy in oncology. Strategies to improve the quality of care by incorporating value-based approaches are discussed: use of composite tools to assess the value of drugs, alternative dosing strategies, and the use of Health Technology Assessment in regulatory procedures. We propose that there must be a greater emphasis on value of therapy in determining its use and its cost.
机构:
Wayne State Univ, Dept Oncol, Karmanos Canc Inst, Detroit, MI USAWayne State Univ, Dept Oncol, Karmanos Canc Inst, Detroit, MI USA
Seymour, Erlene K.
de Souza, Jonas A.
论文数: 0引用数: 0
h-index: 0
机构:
Humana, Louisville, KY USAWayne State Univ, Dept Oncol, Karmanos Canc Inst, Detroit, MI USA
de Souza, Jonas A.
Fendrick, A. Mark
论文数: 0引用数: 0
h-index: 0
机构:
Univ Michigan, Dept Internal Med, Ctr Value Based Insurance Design, Ann Arbor, MI 48109 USAWayne State Univ, Dept Oncol, Karmanos Canc Inst, Detroit, MI USA
机构:
Takeda Pharmaceut Co Ltd, Japan Pharm Business Unit, Market Access Publ Affairs & Patient Experience, Tokyo, Japan
Univ Tokyo, Grad Sch Pharmaceut Sci, Dept Hlth Econ & Outcomes Res, Tokyo, Japan
Takeda Pharmaceut Co Ltd, Tokyo, JapanTakeda Pharmaceut Co Ltd, Japan Pharm Business Unit, Market Access Publ Affairs & Patient Experience, Tokyo, Japan
Takami, Akina
Kato, Masafumi
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h-index: 0
机构:
Takeda Pharmaceut Co Ltd, Japan Pharm Business Unit, Market Access Publ Affairs & Patient Experience, Tokyo, JapanTakeda Pharmaceut Co Ltd, Japan Pharm Business Unit, Market Access Publ Affairs & Patient Experience, Tokyo, Japan
Kato, Masafumi
Deguchi, Hisato
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h-index: 0
机构:
Takeda Pharmaceut Co Ltd, Japan Pharm Business Unit, Market Access Publ Affairs & Patient Experience, Tokyo, JapanTakeda Pharmaceut Co Ltd, Japan Pharm Business Unit, Market Access Publ Affairs & Patient Experience, Tokyo, Japan
Deguchi, Hisato
Igarashi, Ataru
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h-index: 0
机构:
Univ Tokyo, Grad Sch Pharmaceut Sci, Dept Hlth Econ & Outcomes Res, Tokyo, Japan
Yokohama City Univ, Sch Med, Dept Publ Hlth, Yokohama, JapanTakeda Pharmaceut Co Ltd, Japan Pharm Business Unit, Market Access Publ Affairs & Patient Experience, Tokyo, Japan
机构:
Univ Cattolica Sacro Cuore, Fdn Policlin Univ A Gemelli, Italian Natl Inst Care & Res IRCCS, Italian Natl Sci Assoc Qual Hlth & Social Care ASI, Rome, ItalyUniv Cattolica Sacro Cuore, Fdn Policlin Univ A Gemelli, Italian Natl Inst Care & Res IRCCS, Italian Natl Sci Assoc Qual Hlth & Social Care ASI, Rome, Italy
机构:
Cardiff & Vale Univ Hlth Board, Palliat & Support Care Dept, Cardiff, Wales
Cardiff Univ, Sch Med, Palliat Care Dept, Cardiff, WalesCardiff & Vale Univ Hlth Board, Palliat & Support Care Dept, Cardiff, Wales
Atkinson, Clea
Hughes, Sian
论文数: 0引用数: 0
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机构:
Cardiff & Vale Univ Hlth Board, Palliat & Support Care Dept, Cardiff, WalesCardiff & Vale Univ Hlth Board, Palliat & Support Care Dept, Cardiff, Wales
Hughes, Sian
Richards, Len
论文数: 0引用数: 0
h-index: 0
机构:
Cardiff & Vale Univ Hlth Board, Execut Team, Cardiff, WalesCardiff & Vale Univ Hlth Board, Palliat & Support Care Dept, Cardiff, Wales
Richards, Len
Sim, Victor M. F.
论文数: 0引用数: 0
h-index: 0
机构:
Cardiff & Vale Univ Hlth Board, Care Elderly Dept, Cardiff, WalesCardiff & Vale Univ Hlth Board, Palliat & Support Care Dept, Cardiff, Wales
Sim, Victor M. F.
Phillips, Julie
论文数: 0引用数: 0
h-index: 0
机构:
Cardiff & Vale Univ Hlth Board, Cardiol Dept, Cardiff, WalesCardiff & Vale Univ Hlth Board, Palliat & Support Care Dept, Cardiff, Wales
Phillips, Julie
John, Imogen J.
论文数: 0引用数: 0
h-index: 0
机构:
Cardiff & Vale Univ Hlth Board, Palliat & Support Care Dept, Cardiff, WalesCardiff & Vale Univ Hlth Board, Palliat & Support Care Dept, Cardiff, Wales
John, Imogen J.
Yousef, Zaheer
论文数: 0引用数: 0
h-index: 0
机构:
Cardiff & Vale Univ Hlth Board, Cardiol Dept, Cardiff, Wales
Cardiff Univ, Sch Med, Cardiol Dept, Cardiff, WalesCardiff & Vale Univ Hlth Board, Palliat & Support Care Dept, Cardiff, Wales
机构:
Los Angeles Cty Harbor UCLA Med Ctr, Dept Orthopaed Surg, Los Angeles, CA USALos Angeles Cty Harbor UCLA Med Ctr, Dept Orthopaed Surg, Los Angeles, CA USA
Sambare, Tanmaya D.
Vega, Akasha B.
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机构:
Kaiser Permanente Bernard J Tyson Sch Med, Dept Orthopaed Surg, Harbor City, CA USALos Angeles Cty Harbor UCLA Med Ctr, Dept Orthopaed Surg, Los Angeles, CA USA
Vega, Akasha B.
Rana, S. Shamtej Singh
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h-index: 0
机构:
Kaiser Permanente Bernard J Tyson Sch Med, Dept Orthopaed Surg, Harbor City, CA USALos Angeles Cty Harbor UCLA Med Ctr, Dept Orthopaed Surg, Los Angeles, CA USA
Rana, S. Shamtej Singh
Navarro, Ronald A.
论文数: 0引用数: 0
h-index: 0
机构:
Kaiser Permanente Bernard J Tyson Sch Med, Dept Orthopaed Surg, Harbor City, CA USALos Angeles Cty Harbor UCLA Med Ctr, Dept Orthopaed Surg, Los Angeles, CA USA