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Synthetic Ni3S2/Ni hybrid architectures as potential contrast agents in MRI
被引:1
|作者:
Ma, J.
[1
]
Chen, K.
[1
]
机构:
[1] Qingdao Univ Sci & Technol, Coll Mat Sci & Engn, Lab Funct & Biomed Nanomat, Qingdao 266042, Peoples R China
基金:
中国国家自然科学基金;
关键词:
magnetic resonance imaging;
contrast agent;
nickel;
superparamagnetism;
MAGNETIC NANOPARTICLES;
HYPERTHERMIA;
DESIGN;
PHASE;
SIZE;
D O I:
10.1088/2053-1591/3/4/045005
中图分类号:
T [工业技术];
学科分类号:
08 ;
摘要:
Traditional magnetic resonance imaging (MRI) contrast agents mainly include superparamagnetic (SPM) iron oxide nanoparticle as T-2 contrast agent for liver and paramagnetic Gd (III)-chelate as T-1 contrast agent for all organs. In this work, weak ferromagnetic kale-like and SPM cabbage-like Ni3S2@Ni hybrid architectures were synthesized and evaluated as potential T-1 MRI contrast agents. Their relatively small r(2)/r(1) ratios of 2.59 and 2.38, and high r(1) values of 11.27 and 4.89 mmol(-1) L s(-1) (for the kale-like and cabbage-like Ni3S2@Ni, respectively) will shed some light on the development of new-type MRI contrast agents.
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