Investigating direct routes to an advanced intermediate for the synthesis of C-20 diterpene alkaloids

被引：17

作者：

Williams, CM ^{[1
]}

Mander, LN

Bernhardt, PV

Willis, AC

机构：

[1] Univ Queensland, Sch Mol & Microbial Sci, St Lucia, Qld 4072, Australia

[2] Australian Natl Univ, Res Sch Chem, Canberra, ACT, Australia

来源：

TETRAHEDRON | 2005年 / 61卷 / 15期

关键词：

diterpene alkaloids; silver (I); intramolecular Friedel-Crafts arylation; 3-azabicyclo[3.3.1]nonane;

D O I：

10.1016/j.tet.2005.02.014

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Rapid access to the ABCE ring system of the C-20 diterpene alkaloids was achieved by silver (I) promoted intramolecular Friedel-Crafts arylation of a functional group specific 5-bromo-3-azabicyclo[3.3.1]nonane derivative. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：3759 / 3769

页数：11

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