PRACTICALLY USABLE C3 BUILDING BLOCKS FOR THE SYNTHESES OF NITRO HETEROCYCLES

被引：10

作者：

Nishiwaki, Nagatoshi ^{[1
]}

Hirao, Shotaro ^{[1
]}

Sawayama, Jun ^{[1
]}

Saigo, Kazuhiko ^{[1
]}

机构：

[1] Kochi Univ Technol, Sch Environm Sci & Engn, Kochi 7828502, Japan

来源：

HETEROCYCLES | 2012年 / 84卷 / 01期

关键词：

Nitromalonaldehyde; Nitropyrimidinone; Formylnitroenamine; Azadienamine; Dinitropyridone; DEFICIENT PYRIDONE DERIVATIVES; BETA-DIKETIMINATE LIGANDS; RING TRANSFORMATION; NUCLEOPHILIC REACTION; SODIUM NITROMALONALDEHYDE; 1-SUBSTITUTED 3,5-DINITRO-2-PYRIDONES; FUNCTIONAL-GROUPS; ANALOGS; KETONES; 2-NITROMALONALDEHYDE;

D O I：

10.3987/REV-11-SR(P)3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Nitromalonaldehyde (NMA-H) is one of useful synthons for synthesizing nitro compounds. However, NMA-H itself cannot be practically employed because of its unstable property. Therefore, sodium salt of NMA-H (NMA-Na) has been used as its synthetic equivalent from old time, and NMA-Na is still important even now albeit several restrictions with regard to safety and treatability. On the other hand, dinitropyridone, nitropyrimidinone and dinitropyrazole can be employed in place of NMA-Na for the same purpose, and furthermore azadienamines, formylnitroenamines and dinitropyrazole also serve as the synthetic equivalents of NMA-H, which are usable in common organic solvents with safety. These reagents condense with dinucleophiles to afford various kinds of nitro compounds.

引用

页码：115 / 134

页数：20