Atrial Fibrillation After Gastrointestinal Surgery: Incidence and Associated Risk Factors

被引:12
作者
Heywood, Emily G. [1 ]
Drake, Thomas M. [2 ]
Bradburn, Mike [3 ]
Lee, Justin [4 ]
Wilson, Matthew J. [5 ]
Lee, Matthew J. [6 ]
机构
[1] Sheffield Teaching Hosp, Dept Gen Surg, Sheffield, S Yorkshire, England
[2] Univ Edinburgh, Dept Clin Surg, Edinburgh, Midlothian, Scotland
[3] Univ Sheffield, Sch Hlth & Related Res ScHARR, Clin Trials Res Unit, Sheffield, S Yorkshire, England
[4] Sheffield Teaching Hosp, Dept Cardiol, Sheffield, S Yorkshire, England
[5] Univ Sheffield, Sch Hlth & Related Res ScHARR, Anaesthesia, Sheffield, S Yorkshire, England
[6] Sheffield Teaching Hosp, Dept Gen Surg, Sheffield, S Yorkshire, England
关键词
Atrial fibrillation; General surgery; Risk factors; THORACIC-SURGERY; NONCARDIAC SURGERY; STROKE; PREVALENCE; UK;
D O I
10.1016/j.jss.2019.01.017
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background: Atrial fibrillation (AF) is a common dysrhythmia that can occur after major physiological stress including surgery (postoperative AF). There are few data on post-operative AF after abdominal surgery. We set out to define the incidence of de novo post-operative AF after abdominal surgery and associated risk factors. Methods: The Patient History Integrated Data store administrative database was interrogated for patients aged >= 65 y undergoing abdominal surgery from April 2012 to April 2014. Patients with pre-existing AF were excluded. The primary outcome was diagnosis of AF. Results: Two thousand nine hundred and sixty-seven cases were included of whom 187 developed postoperative AF within 90 d (6.3%). The rate of postoperative AF varied by operation and was highest in small bowel resection (17.2%) and lowest in biliary surgery (4.8%). Median time to detection of postoperative AF was 32 d. Patients who developed postoperative AF were significantly older than those who did not develop AF (median age 75.3 y versus 72.4 y, P < 0.01). Logistic regression modeling found increasing age (odds ratio [OR] 1.03 [confidence interval {CI} 1.01-1.06], hypertension OR 1.73 [CI 1.19-2.51]), congestive cardiac failure (OR 3.04 [CI 1.88-4.92], and vascular disease OR 2.29 [CI 1.39-3.37]) were predictive of the development of postoperative AF within 30 d. The area under the curve for this model was 0.733. Conclusions: Postoperative AF affects a significant number of patients after abdominal surgery. Demographics such as history of cardiovascular disease might aid prediction of postoperative AF. Postoperative AF is mostly identified after discharge, suggesting the need for postoperative screening. (C) 2019 Elsevier Inc. All rights reserved.
引用
收藏
页码:23 / 28
页数:6
相关论文
共 25 条
[1]   The epidemiology of cardiovascular disease in the UK 2014 [J].
Bhatnagar, Prachi ;
Wickramasinghe, Kremlin ;
Williams, Julianne ;
Rayner, Mike ;
Townsend, Nick .
HEART, 2015, 101 (15) :1182-1189
[2]   Systematic review of discharge coding accuracy [J].
Burns, E. M. ;
Rigby, E. ;
Mamidanna, R. ;
Bottle, A. ;
Aylin, P. ;
Ziprin, P. ;
Faiz, O. D. .
JOURNAL OF PUBLIC HEALTH, 2012, 34 (01) :138-148
[3]   A systematic review of the incidence of and risk factors for postoperative atrial fibrillation following general surgery [J].
Chebbout, R. ;
Heywood, E. G. ;
Drake, T. M. ;
Wild, J. R. L. ;
Lee, J. ;
Wilson, M. ;
Lee, M. J. .
ANAESTHESIA, 2018, 73 (04) :490-498
[4]   Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD): The TRIPOD statement [J].
Collins, G. S. ;
Reitsma, J. B. ;
Altman, D. G. ;
Moons, K. G. M. .
BRITISH JOURNAL OF CANCER, 2015, 112 (02) :251-259
[5]   Effects of extended-release metoprolol succinate inpatients undergoing non-cardiac surgery (POISE trial):: a randomised controlled trial [J].
Devereaux, P. J. ;
Yang, Homer ;
Yusuf, Salim ;
Guyatt, Gordon ;
Leslie, Kate ;
Villar, Juan Carlos ;
Xavier, Denis ;
Chrolavicius, Susan ;
Greenspan, Launi ;
Pogue, Janice ;
Pais, Prem ;
Liu, Lisheng ;
Xu, Shouchun ;
Malaga, German ;
Avezum, Alvaro ;
Chan, Matthew ;
Montori, Victor M. ;
Jacka, Mike ;
Choi, Peter .
LANCET, 2008, 371 (9627) :1839-1847
[6]   An update on atrial fibrillation in 2014: From pathophysiology to treatment [J].
Ferrari, R. ;
Bertini, M. ;
Blomstrom-Lundqvist, C. ;
Dobrev, D. ;
Kirchhof, P. ;
Pappone, C. ;
Ravens, U. ;
Tamargo, J. ;
Tavazzi, L. ;
Vicedomini, G. G. .
INTERNATIONAL JOURNAL OF CARDIOLOGY, 2016, 203 :22-29
[7]   The-174G/C interleukin-6 polymorphism influences postoperative interleukin-6 levels and postoperative atrial fibrillation. Is atrial fibrillation an inflammatory complication? [J].
Gaudino, M ;
Andreotti, F ;
Zamparelli, R ;
Di Castelnuovo, A ;
Nasso, G ;
Burzotta, F ;
Iacoviello, L ;
Donati, MB ;
Schiavello, R ;
Maseri, A ;
Possati, G .
CIRCULATION, 2003, 108 (10) :195-199
[8]   Prognosis research strategy (PROGRESS) 1: A framework for researching clinical outcomes [J].
Hemingway, Harry ;
Croft, Peter ;
Perel, Pablo ;
Hayden, Jill A. ;
Abrams, Keith ;
Timmis, Adam ;
Briggs, Andrew ;
Udumyan, Ruzan ;
Moons, Karel G. M. ;
Steyerberg, Ewout W. ;
Roberts, Ian ;
Schroter, Sara ;
Altman, Douglas G. ;
Riley, Richard D. .
BMJ-BRITISH MEDICAL JOURNAL, 2013, 346
[9]  
Joshi Kirti K, 2015, Hosp Pract (1995), V43, P235, DOI 10.1080/21548331.2015.1096181
[10]   Coding of stroke and stroke risk factors using International Classification of Diseases, revisions 9 and 10 [J].
Kokotailo, RA ;
Hill, MD .
STROKE, 2005, 36 (08) :1776-1781