New derivatives of 1H-imidazo[4,5-b]pyridine-2(3H)-thione.: Synthesis of thiosemicarbazides and their cyclic analogues

被引：0

作者：

Liszkiewicz, Hanna ^{[1
]}

机构：

[1] Wroclaw Med Univ, Dept Drugs Technol, PL-50140 Wroclaw, Poland

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2008年 / 183卷 / 06期

关键词：

1H; 3H-2-thioxoimidazo[4,5-b] pyridine derivatives; hydrazide; structures; synthesis; thiazole; thiosemicarbazide;

D O I：

10.1080/10426500701648077

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A series of 2-(arylthiosemicarbazide)-imidazo[4,5-b]pyridines (6-9) were prepared by reaction of 2-(carbazoylalkylthio)-imidazo[4,5-b]pyridines (4 and 5) with selected arylisothiocyanates. The thiosemicarbazides 6 and 7 were cyclized with 2-bromoacetophenone to give the derivatives of imidazo[4,5-b]pyridine 10 and 11. Compounds (2-11) were characterized by elemental analysis as well as IR and H-s1 NMR spectroscopy.

引用

页码：1402 / 1409

页数：8

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