Sesquiterpene glucosides from anti-leukotriene B4 release fraction of Taraxacum officinale

被引：22
|
作者：
Kashiwada, Y
Takanaka, K
Tsukada, H
Miwa, Y
Taga, T
Tanaka, S
Ikeshiro, Y [1 ]
机构：
[1] Niigata Coll Pharm, Kamishinei Cho, Niigata 9502081, Japan
[2] Kyoto Univ, Grad Sch Pharmaceut Sci, Sakyo Ku, Yoshida, Kyoto 6068304, Japan
[3] Tokyo Univ Agr, Fac Appl Biosci, Setagaya Ku, Sakuragoaka, Tokyo 1568502, Japan
来源：
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2001年 / 3卷 / 03期
关键词：
Taraxacum officinale; Compositae; anti-leukotriene B-4 formation; germacrane; sesquiterpene;
D O I：
10.1080/10286020108041390
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Chemical examination of the MeOH extract of the root of Taraxacum officinale, which exhibited inhibitory activity on the formation of leukotriene Bq from activated human neutrophils, has resulted in the isolation of 14-O-beta -D-glucosyl-11,13-dihydro-taraxinic acid (1) and 14-O-beta -D-glucosyl-taraxinic acid (2). The absolute stereostructure of 1 has been established by X-ray chrystallographic examination.
引用
收藏
页码：191 / 197
页数：7
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