The regiospecific Fischer indole reaction in choline chloride•2ZnCl2 with product isolation by direct sublimation from the ionic liquid

被引：121
作者：
Morales, RC [1 ]
Tambyrajah, V [1 ]
Jenkins, PR [1 ]
Davies, DL [1 ]
Abbott, AP [1 ]
机构：
[1] Univ Leicester, Dept Chem, Green Chem Res Grp, Leicester LE1 7RH, Leics, England
来源：
CHEMICAL COMMUNICATIONS | 2004年 / 02期
关键词：
D O I：
10.1039/b313655h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The Fischer indole synthesis occurs in high yield with one equivalent of the ionic liquid choline chloride.2ZnCl(2); exclusive formation of 2,3-disubstituted indoles is observed in the reaction of alkyl methyl ketones, and the products readily sublime directly from the ionic liquid.
引用
收藏
页码：158 / 159
页数：2
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