The regiospecific Fischer indole reaction in choline chloride•2ZnCl2 with product isolation by direct sublimation from the ionic liquid

被引：122

作者：

Morales, RC ^{[1
]}

Tambyrajah, V ^{[1
]}

Jenkins, PR ^{[1
]}

Davies, DL ^{[1
]}

Abbott, AP ^{[1
]}

机构：

[1] Univ Leicester, Dept Chem, Green Chem Res Grp, Leicester LE1 7RH, Leics, England

来源：

CHEMICAL COMMUNICATIONS | 2004年 / 02期

关键词：

D O I：

10.1039/b313655h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The Fischer indole synthesis occurs in high yield with one equivalent of the ionic liquid choline chloride.2ZnCl(2); exclusive formation of 2,3-disubstituted indoles is observed in the reaction of alkyl methyl ketones, and the products readily sublime directly from the ionic liquid.

引用

页码：158 / 159

页数：2

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