NIR-absorbing dye functionalized hollow mesoporous silica nanoparticles for combined photothermal-chemotherapy

被引：26

作者：

Zhang, Yuanyuan ^{[1
,2
]}

Qu, Qiuyu ^{[2
]}

Cao, Xiang ^{[1
]}

Zhao, Yanli ^{[2
,3
]}

机构：

[1] Huaihai Inst Technol, Sch Chem Engn, Lianyungang 222005, Peoples R China

[2] Nanyang Technol Univ, Sch Phys & Math Sci, Div Chem & Biol Chem, 21 Nanyang Link, Singapore 637371, Singapore

[3] Nanyang Technol Univ, Sch Mat Sci & Engn, Singapore 639798, Singapore

来源：

CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 88期

关键词：

DRUG-DELIVERY; MULTIDRUG-RESISTANCE; THERAPY; CANCER; MICELLES; AGENTS; PH;

D O I：

10.1039/c7cc07897h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Multifunctional hollow mesoporous silica nanoparticles were constructed by firstly loading with doxorubicin and then capping with disulfide linked beta-cyclodextrin followed by complexation with adamantane functionalized indocyanine dye, showing improved anticancer efficacy through combined photothermal-chemotherapy.

引用

页码：12032 / 12035

页数：4

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