Excellent enantio-selective enclathration of (2R,3S)-3-methyl-2-pentanol in channel-like cavity of 3-epideoxycholic acid, interpreted by the four-location model for chiral recognition

被引:25
作者
Kato, K [1 ]
Aburaya, K [1 ]
Miyake, Y [1 ]
Sada, K [1 ]
Tohnai, N [1 ]
Miyata, M [1 ]
机构
[1] Osaka Univ, Grad Sch Engn, Dept Mat & Life Sci, Suita, Osaka 5650871, Japan
关键词
D O I
10.1039/b309755b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Pure ( 2R, 3S)- 3- methyl- 2- pentanol is resolved from the racemates by a steroidal host; the interpretation of the recognition mechanism based on the crystal structure reveals that CH/ O interaction between the host and guest plays a decisive role in enantio- selective enclathration of the small aliphatic secondary alcohol.
引用
收藏
页码:2872 / 2873
页数:2
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