A prospective study of passive smoking and risk of diabetes in a cohort of workers - The High-Risk and Population Strategy for Occupational Health Promotion (HIPOP-OHP) Study

被引:54
作者
Hayashino, Yasuaki [1 ]
Fukuhara, Shunichi [1 ]
Okamura, Tomonori [2 ]
Yamato, Hiroshi
Tanaka, Hideo [3 ]
Tanaka, Taichiro [4 ]
Kadowaki, Takashi [2 ]
Ueshima, Hirotsugu [2 ]
机构
[1] Kyoto Univ, Grad Sch Med, Dept Epidemiol & Healthcare Res, Sakyo Ku, Kyoto 6068501, Japan
[2] Shiga Univ Med Sci, Shiga, Japan
[3] Osaka Med Ctr Canc & Cardiovasc Dis, Osaka, Japan
[4] Univ Yamanashi, Yamanashi, Japan
关键词
D O I
10.2337/dc07-1905
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVE - We investigated the impact of active smoking and exposure to passive smoke on the risk of developing diabetes. RESEARCH DESIGN AND METHODS - Data were analyzed from a cohort of participants in the High-Risk and Population Strategy for Occupational Health Promotion Study (HIPOP-OHP) conducted in japan from 1999 to 2004. Active and passive smoking status in the workplace was evaluated at baseline. RESULTS - Of 6,498 participants (20.9% women), a total of 229 diabetes cases were reported over a median 3.4 years of follow-up. In the workplace, compared with zero-exposure subjects, the multivariable-adjusted hazard ratios of developing diabetes were 1.81 (95% Cl 1.06-3.08, P = 0.028) for present passive subjects and 1.99 (1.29-3.04, P = 0.002) for present active smokers. CONCLUSIONS - In this cohort, exposure to passive smoke in the workplace was associated with an increased risk of diabetes after adjustment for a large number of possible confounders,
引用
收藏
页码:732 / 734
页数:3
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