T regulatory cells and allergy

被引：25
|
作者：
Taylor, A [1 ]
Verhagen, J [1 ]
Akdis, CA [1 ]
Akdis, M [1 ]
机构：
[1] Swiss Inst Allergy & Asthma Res, SIAF, CH-7270 Davos, Switzerland
来源：
MICROBES AND INFECTION | 2005年 / 7卷 / 7-8期
关键词：
T regulatory cells; immunotherapy; tolerance; anergy; IgE; T cells;
D O I：
10.1016/j.micinf.2005.03.029
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Anergy, tolerance and active suppression may not be independent events, but rather involve similar mechanisms and cell types in immune regulation. Induction of allergen-specific T-Reg cells seems essential for maintaining a healthy immune response towards allergens. By utilizing multiple secreted cytokines and surface molecules, antigen-specific T-Reg cells may re-direct an inappropriate immune response against allergens or auto-antigens. (c) 2005 Elsevier SAS. All rights reserved.
引用
收藏
页码：1049 / 1055
页数：7
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