T regulatory cells and allergy

被引：25

作者：

Taylor, A ^{[1
]}

Verhagen, J ^{[1
]}

Akdis, CA ^{[1
]}

Akdis, M ^{[1
]}

机构：

[1] Swiss Inst Allergy & Asthma Res, SIAF, CH-7270 Davos, Switzerland

来源：

MICROBES AND INFECTION | 2005年 / 7卷 / 7-8期

关键词：

T regulatory cells; immunotherapy; tolerance; anergy; IgE; T cells;

D O I：

10.1016/j.micinf.2005.03.029

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Anergy, tolerance and active suppression may not be independent events, but rather involve similar mechanisms and cell types in immune regulation. Induction of allergen-specific T-Reg cells seems essential for maintaining a healthy immune response towards allergens. By utilizing multiple secreted cytokines and surface molecules, antigen-specific T-Reg cells may re-direct an inappropriate immune response against allergens or auto-antigens. (c) 2005 Elsevier SAS. All rights reserved.

引用

页码：1049 / 1055

页数：7

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