Dielectrophoresis-Raman spectroscopy system for analysing suspended nanoparticles

被引：47

作者：

Chrimes, Adam F. ^{[1
]}

Kayani, Aminuddin A. ^{[1
]}

Khoshmanesh, Khashayar ^{[2
]}

Stoddart, Paul R.

Mulvaney, Paul ^{[3
,4
,5
]}

Mitchell, Arnan ^{[1
]}

Kalantar-zadeh, Kourosh ^{[1
]}

机构：

[1] RMIT Univ, Sch Elect & Comp Engn, Melbourne, Vic, Australia

[2] Deakin Univ, Ctr Intelligent Syst Res, Geelong, Vic 3217, Australia

[3] Swinburne Univ, Ctr Atom Opt & Ultrafast Spect, Melbourne, Vic, Australia

[4] Univ Melbourne, Sch Chem, Parkville, Vic 3052, Australia

[5] Univ Melbourne, Inst Bio21, Parkville, Vic 3052, Australia

来源：

LAB ON A CHIP | 2011年 / 11卷 / 05期

关键词：

ON-A-CHIP; MICROFLUIDIC SYSTEMS; CARBON NANOTUBES; SURFACE; SCATTERING; SEPARATION; PARTICLES; CELLS; SERS; SINGLE;

D O I：

10.1039/c0lc00481b

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A microfluidic dielectrophoresis platform consisting of curved microelectrodes was developed and integrated with a Raman spectroscopy system. The electrodes were patterned on a quartz substrate, which has insignificant Raman response, and integrated with a microfluidic channel that was imprinted in poly-dimethylsiloxane (PDMS). We will show that this novel integrated system can be efficiently used for the determination of suspended particle types and the direct mapping of their spatial concentrations. We will also illustrate the system's unique advantages over conventional optical systems. Nanoparticles of tungsten trioxide (WO3) and polystyrene were used in the investigations, as they are Raman active and can be homogeneously suspended in water.

引用

页码：921 / 928

页数：8

共 62 条

[1] Multiplexed microfluidic surface-enhanced Raman spectroscopy [J].

Abu-Hatab, Nahla A. ;

John, Joshy F. ;

Oran, Jenny M. ;

Sepaniak, Michael J. .

APPLIED SPECTROSCOPY, 2007, 61 (10) :1116-1122

[2] Quantitative online detection of low-concentrated drugs via a SERS microfluidic system [J].

Ackermann, Katrin R. ;

Henkel, Thomas ;

Popp, Juergen .

CHEMPHYSCHEM, 2007, 8 (18) :2665-2670

[3] DIELECTRIC APPROACH TO SUSPENSIONS OF ELLIPSOIDAL PARTICLES COVERED WITH A SHELL IN PARTICULAR REFERENCE TO BIOLOGICAL CELLS [J].

ASAMI, K ;

HANAI, T ;

KOIZUMI, N .

JAPANESE JOURNAL OF APPLIED PHYSICS, 1980, 19 (02) :359-365

[4] Chemical imaging in a surface forces apparatus: Confocal Raman spectroscopy of confined poly(dimethylsiloxane) [J].

Bae, SC ;

Lee, H ;

Lin, ZQ ;

Granick, S .

LANGMUIR, 2005, 21 (13) :5685-5688

[5] Synthesis and characterization of micrometer-sized, polyaniline-coated polystyrene latexes [J].

Barthet, C ;

Armes, SP ;

Lascelles, SF ;

Luk, SY ;

Stanley, HME .

LANGMUIR, 1998, 14 (08) :2032-2041

[6] Control and modeling of the dielectrophoretic assembly of on-chip nanoparticle wires [J].

Bhatt, KH ;

Velev, OD .

LANGMUIR, 2004, 20 (02) :467-476

[7] NUMERICAL-ANALYSIS OF THE HANAI FORMULA - EXPERIMENTAL APPLICATION TO DIELECTRIC PROPERTIES OF MICROEMULSIONS [J].

BONED, C ;

PEYRELASSE, J ;

CLAUSSE, M ;

LAGOURETTE, B ;

ALLIEZ, J ;

BABIN, L .

COLLOID AND POLYMER SCIENCE, 1979, 257 (10) :1073-1082

[8] Recent advances in surface-enhanced Raman scattering detection technology for microfluidic chips [J].

Chen, Lingxin ;

Choo, Jaebum .

ELECTROPHORESIS, 2008, 29 (09) :1815-1828

[9] Hotspot-Induced Transformation of Surface-Enhanced Raman Scattering Fingerprints [J].

Chen, Tao ;

Wang, Hong ;

Chen, Gang ;

Wang, Yong ;

Feng, Yuhua ;

Teo, Wei Shan ;

Wu, Tom ;

Chen, Hongyu .

ACS NANO, 2010, 4 (06) :3087-3094

[10] On-Chip Immunoassay Using Surface-Enhanced Raman Scattering of Hollow Gold Nanospheres [J].

Chon, Hyangah ;

Lim, Chaesung ;

Ha, Seung-Mo ;

Ahn, Yoomin ;

Lee, Eun Kyu ;

Chang, Soo-Ik ;

Seong, Gi Hun ;

Choo, Jaebum .

ANALYTICAL CHEMISTRY, 2010, 82 (12) :5290-5295

← 1 2 3 4 5 6 7 →