The Radiological Differentiation of Hypervascular Intrahepatic Cholangiocarcinoma from Hepatocellular Carcinoma with a Focus on the CT Value on Multi-phase Enhanced CT

被引：8
作者：
Sano, Shusei [1 ]
Yamamoto, Yusuke [1 ]
Sugiura, Teiichi [1 ]
Okamura, Yukiyasu [1 ]
Ito, Takaaki [1 ]
Ashida, Ryo [1 ]
Ohgi, Katsuhisa [1 ]
Aramaki, Takeshi [2 ]
Nakanuma, Yasuni [3 ]
Uesaka, Katsuhiko [1 ]
机构：
[1] Shizuoka Canc Ctr, Div Hepatobiliary Pancreat Surg, 1007 Shimo Nagakubo, Sunto Nagaizumi, Shizuoka 4118777, Japan
[2] Shizuoka Canc Ctr, Div Intervent Radiol, Shizuoka, Japan
[3] Shizuoka Canc Ctr, Div Pathol, Shizuoka, Japan
来源：
ANTICANCER RESEARCH | 2018年 / 38卷 / 09期
关键词：
Intrahepatic cholangiocarcinoma; hepatocellular carcinoma; multidetector computed tomography; differential diagnosis; COMPUTED-TOMOGRAPHY; PERIPHERAL CHOLANGIOCARCINOMA; RESECTION; MASS; OUTCOMES; PATTERN; IMPACT;
D O I：
10.21873/anticanres.12884
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Background/Aim: This study aimed to investigate whether hypervascular intrahepatic cholangiocarcinoma (HICC) can be differentiated from hepatocellular carcinoma (HCC). Materials and Methods: Among 100 patients with intrahepatic cholangiocarcinoma, 22 patients were diagnosed with HICC based on the computed tomography (CT) value in the late arterial phase as follows: the CT value of the tumor >= that of the liver parenchyma. The CT values of the HICC were compared to those of HCC cases (n=120). Results: The CT value of HICC was lower in the unenhanced phase (UP) (p=0.016) and higher in the equilibrium phase (EP) (p<0.001) in comparison to HCC. The non-tumorous liver (odds ratio [OR]: 6.35, p=0.002) and an E/U ratio (the mean CT value of the tumor in the EP to that in the UP) of >2.3 (OR=13.1, p<0.001) were independent diagnostic factors for differentiating HICC from HCC. Conclusion: E/U ratio is useful for differentiating between HICC and HCC.
引用
收藏
页码：5505 / 5512
页数：8
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