Regio- and Stereoselective Copper(II)-Catalyzed Hydrosilylation of Activated Allenes in Water: Access to Vinylsilanes

被引：30

作者：

Pashikanti, Srinath ^{[1
]}

Calderone, Joseph A. ^{[1
]}

Nguyen, Matthew K. ^{[1
]}

Sibley, Christopher D. ^{[1
]}

Santos, Webster L. ^{[1
]}

机构：

[1] Virginia Tech, Dept Chem, Blacksburg, VA 24061 USA

来源：

ORGANIC LETTERS | 2016年 / 18卷 / 10期

基金：

美国国家科学基金会;

关键词：

SI-B BOND; SILYL CONJUGATE ADDITIONS; INTERNAL ALKYNES; TERMINAL ALKYNES; CATALYZED HYDROSILYLATION; REGIOSELECTIVE HYDROSILYLATION; ENANTIOSELECTIVE SYNTHESIS; ORGANIC-SYNTHESIS; BETA-BORYLATION; GAMMA-ADDITIONS;

D O I：

10.1021/acs.orglett.6b00981

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

By using catalytic amounts of copper(II), 4-picoline, and dimethylphenylsilylpinacol borane, a series of allenoates were silylated on the beta carbon in good to excellent yields and high (E)-selectivity. The mild and efficient silylation method is conducted in water under atmospheric conditions to afford vinylsilanes.

引用

页码：2443 / 2446

页数：4

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