Nanogels: A novel approach in antimicrobial delivery systems and antimicrobial coatings

被引：98

作者：

Keskin, Damla ^{[1
]}

Zu, Guangyue ^{[1
]}

Forson, Abigail M. ^{[1
]}

Tromp, Lisa ^{[1
]}

Sjollema, Jelmer ^{[1
]}

van Rijn, Patrick ^{[1
]}

机构：

[1] Univ Groningen, Univ Med Ctr Groningen, Dept Biomed Engn, WJ Kolff Inst, Antonius Deusinglaan 1, NL-9713 AV Groningen, Netherlands

来源：

BIOACTIVE MATERIALS | 2021年 / 6卷 / 10期

关键词：

Nanogels; Coatings; Antibacterial activity; Antifouling; Biocompatibility; CONTROLLED/LIVING RADICAL POLYMERIZATION; INVERSE MICROEMULSION POLYMERIZATION; DRUG-DELIVERY; SILVER NANOPARTICLES; ESSENTIAL OILS; ACID NANOGEL; THERMORESPONSIVE NANOGELS; BIOMEDICAL APPLICATIONS; VANCOMYCIN RESISTANCE; RESPONSIVE NANOGELS;

D O I：

10.1016/j.bioactmat.2021.03.004

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The implementation of nanotechnology to develop efficient antimicrobial systems has a significant impact on the prospects of the biomedical field. Nanogels are soft polymeric particles with an internally cross-linked structure, which behave as hydrogels and can be reversibly hydrated/dehydrated (swollen/shrunken) by the dispersing solvent and external stimuli. Their excellent properties, such as biocompatibility, colloidal stability, high water content, desirable mechanical properties, tunable chemical functionalities, and interior gel-like network for the incorporation of biomolecules, make them fascinating in the field of biological/biomedical applications. In this review, various approaches will be discussed and compared to the newly developed nanogel technology in terms of efficiency and applicability for determining their potential role in combating infections in the biomedical area including implant-associated infections.

引用

页码：3634 / 3657

页数：24

共 287 条

[1] Functional Microgels: Recent Advances in Their Biomedical Applications [J].