Histone H2AX in DNA damage and repair

被引:1
|
作者
Sedelnikova, OA [1 ]
Pilch, DR [1 ]
Redon, C [1 ]
Bonner, WM [1 ]
机构
[1] NCI, Mol Pharmacol Lab, Ctr Canc Res, NIH, Bethesda, MD 20892 USA
关键词
gamma-H2AX; DNA double strand breaks; ionizing radiation;
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:233 / 235
页数:3
相关论文
共 50 条
  • [31] Constitutive histone H2AX phosphorylation and ATM activation, the reporters of DNA damage by endogenous oxidants
    Darzynkiewicz, Zbigniew
    CELL CYCLE, 2009, 8 (10) : 1471 - 1472
  • [32] Focus on histone variant H2AX: To be or not to be
    Yuan, Jingsong
    Adamski, Rachel
    Chen, Junjie
    FEBS LETTERS, 2010, 584 (17) : 3717 - 3724
  • [33] Synchronization in the cell cycle by inhibitors of DNA replication induces histone H2AX phosphorylation: an indication of DNA damage
    Kurose, A
    Tanaka, T
    Huang, X
    Traganos, F
    Darzynkiewicz, Z
    CELL PROLIFERATION, 2006, 39 (03) : 231 - 240
  • [34] Low level phosphorylation of histone H2AX on serine 139 (γH2AX) is not associated with DNA double-strand breaks
    Rybak, Paulina
    Hoang, Agnieszka
    Bujnowicz, Lukasz
    Bernas, Tytus
    Berniak, Krzysztof
    Zarebski, Miroslaw
    Darzynkiewicz, Zbigniew
    Dobrucki, Jerzy
    ONCOTARGET, 2016, 7 (31) : 49574 - 49587
  • [35] Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks
    Celeste, A
    Fernandez-Capetillo, O
    Kruhlak, MJ
    Pilch, DR
    Staudt, DW
    Lee, A
    Bonner, RF
    Bonner, WM
    Nussenzweig, A
    NATURE CELL BIOLOGY, 2003, 5 (07) : 675 - U51
  • [36] Retention of γH2AX foci as an indication of lethal DNA damage
    Olive, Peggy L.
    RADIOTHERAPY AND ONCOLOGY, 2011, 101 (01) : 18 - 23
  • [37] PNU-166196 induces DNA damage measured by histone H2AX phosphorylation independently of the nucleotide excision repair pathways.
    Guirouilh-Barbat, Jose
    Takagi, Kazutaka
    Von Hoff, Daniel D.
    Pommier, Yves
    MOLECULAR CANCER THERAPEUTICS, 2007, 6 (12) : 3456S - 3457S
  • [38] Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks
    Arkady Celeste
    Oscar Fernandez-Capetillo
    Michael J. Kruhlak
    Duane R. Pilch
    David W. Staudt
    Alicia Lee
    Robert F. Bonner
    William M. Bonner
    André Nussenzweig
    Nature Cell Biology, 2003, 5 : 675 - 679
  • [39] The γH2AX DNA damage assay from a drop of blood
    Daniel Heylmann
    Bernd Kaina
    Scientific Reports, 6
  • [40] Phosphorylated histone H2Ax in PBMCs as a pharmacodynamic surrogate response to DNA damage by topoisomerase I inhibitors
    Ji, Jay
    Yutzy, Will
    Putvatana, Ravithat
    Zhang, Yiping
    Kinders, Robert J.
    Parchment, Ralph E.
    Hollingshead, Melinda G.
    Tomaszewski, Joseph E.
    Doroshow, James H.
    MOLECULAR CANCER THERAPEUTICS, 2007, 6 (12) : 3542S - 3542S