Low photobleaching and high emission depletion efficiency: the potential of AIE luminogen as fluorescent probe for STED microscopy

被引：39
|
作者：
Yu, Jiaxin [1 ]
Sun, Xianhe [1 ]
Cai, Fuhong [1 ]
Zhu, Zhenfeng [1 ]
Qin, Anjun [2 ]
Qian, Jun [1 ]
Tang, Benzhong [2 ,3 ]
He, Sailing [1 ]
机构：
[1] Zhejiang Univ, Ctr Opt & Elect Res, State Key Lab Modern Opt Instrumentat, Zhejiang Prov Key Lab Sensing Technol, Hangzhou 310058, Zhejiang, Peoples R China
[2] S China Univ Technol, SCUT HKUST Joint Res Lab, State Key Lab Luminescent Mat & Devices, Guangdong Innovat Res Team, Guangzhou 510640, Guangdong, Peoples R China
[3] Hong Kong Univ Sci & Technol, Dept Chem, Kowloon, Hong Kong, Peoples R China
来源：
OPTICS LETTERS | 2015年 / 40卷 / 10期
基金：
中国国家自然科学基金;
关键词：
AGGREGATION-INDUCED EMISSION; NITROGEN-VACANCY CENTERS; STIMULATED-EMISSION; BIOCOMPATIBLE NANOPARTICLES; ORGANIC DOTS; DIAMOND;
D O I：
10.1364/OL.40.002313
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
We present a preliminary study which explores the potential of aggregation-induced emission (AIE) luminogen as a new fluorescent probe for STED microscopy. Compared with Coumarin 102, which is a commonly used organic fluorophore in STED microscopy, HPS, a typical AIE luminogen, is more resistant to photobleaching. In addition, HPS-doped nanoparticles have higher emission depletion efficiency than Coumarin 102 in organic solution. These two advantages of AIE luminogen can facilitate the improvement of spatial resolution, as well as long-term imaging, in STED microscopy. AIE luminogen will be a promising candidate for STED microscopy in the future. (C) 2015 Optical Society of America
引用
收藏
页码：2313 / 2316
页数：4
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