Molecular diagnosis and therapy for cutaneous leishmaniasis of a returned traveler from Mexico

被引:3
|
作者
Tsai, Pei-Hsuan [1 ]
Chen, Yu-Ting [2 ,3 ]
Liau, Jau-Yu [2 ,3 ]
Huang, Miao-Hui [3 ,4 ,5 ]
Hsu, Hong-Ming [6 ]
Yeong, Eng-Kean [3 ,7 ]
Hung, Chien-Ching [3 ,4 ,6 ]
机构
[1] Far Eastern Mem Hosp, Dept Internal Med, New Taipei, Taiwan
[2] Natl Taiwan Univ Hosp, Dept Pathol, Taipei, Taiwan
[3] Natl Taiwan Univ, Coll Med, 7 Chung Shan South Rd, Taipei, Taiwan
[4] Natl Taiwan Univ Hosp, Dept Internal Med, Taipei, Taiwan
[5] Hualien Tzu Chi Hosp, Buddhist Tzu Chi Med Fdn, Dept Internal Med, Hualien, Taiwan
[6] Natl Taiwan Univ, Coll Med, Dept Trop Med & Parasitol, 1 Jen Ai Rd, Taipei, Taiwan
[7] Natl Taiwan Univ Hosp, Dept Surg, 7 Chung Shan South Rd, Taipei, Taiwan
关键词
Cutaneous leishmaniasis; Ketoconazole; Liposomal amphotericin B; Leishmania mexicana; Taiwan; OLD-WORLD; INFECTIONS; DISEASE; TAIWAN;
D O I
10.1016/j.jmii.2020.07.007
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Leishmaniasis is prevalent in Southern Europe, the Middle East, India, Africa, and Central and South America. Cutaneous leishmaniasis may spontaneously heal over time without treatment; however, risk of visceral dissemination and the impact of cosmetic defect are important concerns. We report a Case of cutaneous leishmaniasis in a patient who ever traveled to Mexico before the onset of a deteriorating wound around the swollen left eyebrow. A diagnosis of infection with Leishmania mexicana was made based on histopathological examination and molecular identification. Systemic treatment with liposomal amphotericin B and ketoconazole were administered with gradual healing of the lesion. Also, this traveler case implicates that the spread of endemic parasitic diseases may be a concealed risk on the public health for Taiwan underlying globalization.
引用
收藏
页码:1154 / 1158
页数:5
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