In vitro and in vivo cytotoxicities and antileishmanial activities of thymol and hemisynthetic derivatives

被引：78

作者：

Robledo, S

Osorio, E

Muñoz, D

Jaramillo, LM

Restrepo, A

Arango, G

Vélez, I

机构：

[1] Univ Antioquia, PECET, Medellin, Colombia

[2] Univ Antioquia, Grp Invest Sustancias Bioactivas, GISB, Medellin, Colombia

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2005年 / 49卷 / 04期

关键词：

D O I：

10.1128/AAC.49.4.1652-1655.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The in vitro and in vivo antileishmanial and cytotoxic activities of thymol and structural derivatives in comparison to those of Glucantime were studied. The results showed here suggest that thymol and hemisynthetic derivatives have promising antileishmanial potential and could be considered as new lead structures in the search for novel antileishmanial drugs.

引用

页码：1652 / 1655

页数：4

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