Syn diastereoselectivity in the synthesis of homoallylamine using crotylsilane in the three-component reaction

被引：38

作者：

Billet, M ^{[1
]}

Klotz, P ^{[1
]}

Mann, A ^{[1
]}

机构：

[1] Fac Pharm Illkirch, URM 7081, Lab Pharmacochim Commun Cellulaire, F-67401 Illkirch Graffenstaden, France

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 04期

关键词：

crotylsilane; three-component; homoallylamines; iminiums; pyrrolidines; piperidines;

D O I：

10.1016/S0040-4039(00)02025-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Crotylsilane was used in a three-component reaction for the synthesis of homoallylamines from aldehydes. A moderate to good syn/anti 5/1 diastereoselectivity was observed. The obtained homoallylamines were transformed into pyrrolidines or piperidines. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：631 / 634

页数：4

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