Pd-catalyzed Auto-Tandem Cascades Based on N -Sulfonylhydrazones: Hetero- and Carbocyclization Processes

被引：34

作者：

Barroso, Raquel ^{[1
]}

Cabal, Maria P. ^{[1
]}

Valdes, Carlos ^{[1
]}

机构：

[1] Univ Oviedo, Dept Quim Organ & Inorgan, Inst Univ Quim Organomet Enrique Moles, C Julian Claveria 8, E-33006 Oviedo, Spain

来源：

SYNTHESIS-STUTTGART | 2017年 / 49卷 / 19期

关键词：

N; -tosylhydrazones; cross-coupling; auto-tandem catalysis; palladium; cascade reactions; CROSS-COUPLING REACTIONS; ONE-POT SYNTHESIS; C BOND FORMATION; 3-COMPONENT SYNTHESIS; EFFICIENT SYNTHESIS; CARBENE INSERTION; HECK REACTION; TOSYLHYDRAZONES; ARYLATION; DIHALOARENES;

D O I：

10.1055/s-0036-1588535

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Pd-catalyzed cross-coupling between N-tosylhydrazones and organic halides is a powerful method for the creation of C-C bonds. This transformation has been included recently in cascade processes in which the same catalyst promotes various independent catalytic steps, a process known as auto-tandem catalysis. This strategy proves to be very useful for the construction of relatively complex carbo- and heterocyclic structures, as well as for the generation of molecular diversity. This short review will cover the different Pd-catalyzed auto-tandem reactions involving N-tosylhydrazones organized by the bond-forming sequence: C-C/C-N and C-C/C-C. Some examples of related tandem reactions leading to acyclic compounds are also highlighted.

引用

页码：4434 / 4447

页数：14

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