Drug-resistant tuberculosis at the University Hospital in Gaziantep, south-eastern Turkey

被引：18

作者：

Balci, I

Dikensoy, O ^{[1
]}

Bayram, A

Filiz, A

机构：

[1] Gaziantep Univ, Sch Med, Dept Pulm Dis, TR-27070 Gaziantep, Turkey

[2] Gaziantep Univ, Sch Med, Dept Microbiol, TR-27070 Gaziantep, Turkey

来源：

JOURNAL OF INTERNATIONAL MEDICAL RESEARCH | 2000年 / 28卷 / 06期

关键词：

drug resistance; tuberculosis; Mycobacterium tuberculosis; Bactec; Turkey;

D O I：

10.1177/147323000002800606

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

We aimed to determine the present status of drug resistance of Mycobacterium tuberculosis at the Gaziantep University Hospital in south-east Turkey. Data for 1995 to 1999 were retrospectively evaluated with respect to smear-positive cases, first positive culture for Mycobacterium tuberculosis for each patient and drug-susceptibility tests for the major antituberculous drugs. Cultures were done using the Bactec 460 TB method. A total of 106 (40.2%) strains were resistant to at least one drug. Single drug resistance was observed in 47 strains (17.8%) and resistance to two or three drugs was found in 28 and 29 strains (10.6 and 11.0%), respectively. Two strains (0.8%) were resistant to all four drugs. While multidrug resistance was observed in 52 (19.7%) strains, resistance to isoniazid + rifampin was observed in 20 (7.6%) strains. This retrospective study showed that combined drug resistance of hi. tuberculosis is highly prevalent in southeastern Turkey. Possible reasons for the failure of current control policies were considered.

引用

页码：300 / 306

页数：7

共 12 条

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