A cluster of salivirus A1 (Picornaviridae) infections in newborn babies with acute gastroenteritis in a neonatal hospital unit in Hungary

被引：10

作者：

Boros, Akos ^{[1
,2
]}

Raab, Margit ^{[3
]}

Karoly, Eva ^{[4
]}

Karai, Adrienn ^{[4
]}

Katai, Andrea ^{[5
]}

Bolba, Nora ^{[1
,2
]}

Pankovics, Peter ^{[1
,2
]}

Reuter, Gabor ^{[1
,2
]}

机构：

[1] ANTSZ Reg Inst State Publ Hlth Serv, Reg Lab Virol, Natl Reference Lab Gastroenter Viruses, Szabadsag Ut 7, H-7623 Pecs, Hungary

[2] Univ Pecs, Pecs, Hungary

[3] ANTSZ Reg Inst State Publ Hlth Serv, Dept Epidemiol, Kecskemet, Hungary

[4] Town Hosp Baja, Dept Pediat, Neonatal Care Unit, Baja, Hungary

[5] ANTSZ Reg Inst State Publ Hlth Serv, Virol Lab, Szeged, Hungary

来源：

ARCHIVES OF VIROLOGY | 2016年 / 161卷 / 06期

基金：

匈牙利科学研究基金会;

关键词：

KLASSEVIRUS; QUANTIFICATION; VIRUSES; GENOME; WATER; SITE;

D O I：

10.1007/s00705-016-2824-9

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Salivirus (family Picornaviridae) may be associated with acute gastroenteritis in humans, but there have been no reports of salivirus outbreaks. Salivirus A1 infection with faecal virus concentrations of 2.1-2.6 x 10(9)/g were identified retrospectively in newborn babies, between the ages of 1.5 and 5 days, with apparent clinical symptoms of diarrhea (100 %), fever (40 %), vomiting (40 %), and loss of appetite (40 %) in a neonatal hospital unit in Hungary in July 2013. The complete genome sequence of the salivirus (including the 5'-terminal end) was determined. Salivirus mono-infection may be associated with gastroenteritis in babies who are a few days old. Salivirus testing should be done in public health laboratories in gastroenteritis outbreaks with unknown etiology.

引用

页码：1671 / 1677

页数：7

共 25 条

[1] Salivirus type 1 and type 2 in patients with acute gastroenteritis, Germany
Aldabbagh, Souhaib
Eckerle, Isabella
Mueller, Andreas
Delwart, Eric L.
Eis-Huebinger, Anna M.
[J]. JOURNAL OF CLINICAL VIROLOGY, 2015, 72 : 16 - 19
[2] Detection and genetic differentiation of human astroviruses: Phylogenetic grouping varies by coding region
Belliot, G
Laveran, H
Monroe, SS
[J]. ARCHIVES OF VIROLOGY, 1997, 142 (07) : 1323 - 1334
[3] Cleavage site analysis in picornaviral polyproteins: Discovering cellular targets by neural networks
Blom, N
Hansen, J
Blaas, D
Brunak, S
[J]. PROTEIN SCIENCE, 1996, 5 (11) : 2203 - 2216
[4] Avian picornaviruses: Molecular evolution, genome diversity and unusual genome features of a rapidly expanding group of viruses in birds
Boros, Akos
Pankovics, Peter
Reuter, Gabor
[J]. INFECTION GENETICS AND EVOLUTION, 2014, 28 : 151 - 166
[5] Novel Positive-Sense, Single-Stranded RNA ( plus ssRNA) Virus with Di-Cistronic Genome from Intestinal Content of Freshwater Carp (Cyprinus carpio)
Boros, Akos
Pankovics, Peter
Simmonds, Peter
Reuter, Gabor
[J]. PLOS ONE, 2011, 6 (12):
[6] Detection and quantification of classic and emerging viruses by skimmed-milk flocculation and PCR in river water from two geographical areas
Calgua, Byron
Fumian, Tulio
Rusinol, Marta
Rodriguez-Manzano, Jesus
Mbayed, Viviana A.
Bofill-Mas, Silvia
Miagostovich, Marize
Girones, Rosina
[J]. WATER RESEARCH, 2013, 47 (08) : 2797 - 2810
[7] VARNA: Interactive drawing and editing of the RNA secondary structure
Darty, Kevin
Denise, Alain
Ponty, Yann
[J]. BIOINFORMATICS, 2009, 25 (15) : 1974 - 1975
[8] Serological Evidence of Human Klassevirus Infection
Greninger, Alexander L.
Holtz, Lori
Kang, Gagandeep
Ganem, Donald
Wang, David
DeRisi, Joseph L.
[J]. CLINICAL AND VACCINE IMMUNOLOGY, 2010, 17 (10) : 1584 - 1588
[9] The complete genome of klassevirus - a novel picornavirus in pediatric stool
Greninger, Alexander L.
Runckel, Charles
Chiu, Charles Y.
Haggerty, Thomas
Parsonnet, Julie
Ganem, Donald
DeRisi, Joseph L.
[J]. VIROLOGY JOURNAL, 2009, 6
[10] Hall T.A., 1999, IOC world bird list (version 11.1), DOI [10.1021/bk-1999-0734.ch008, DOI 10.14344/IOC.ML.11.1, DOI 10.1021/BK-1999-0734.CH008]

← 1 2 3 →