Multicentric Castleman disease, Kaposi sarcoma, hemophagocytic syndrome, and a novel HHV8-lymphoproliferative disorder

被引:0
|
作者
Yates, Jennifer A. [1 ]
Zakai, Neil A. [2 ,3 ]
Griffith, Rogers C. [4 ]
Wing, Edward J. [5 ]
Schiffman, Fred J. [5 ]
机构
[1] Johns Hopkins Univ Hosp, Dept Internal Med, Baltimore, MD 21287 USA
[2] Univ Vermont, Dept Med, Burlington, VT 05405 USA
[3] Fletcher Allen Hlth Care, Burlington, VT USA
[4] Brown Univ, Dept Pathol, Providence, RI 02912 USA
[5] Brown Univ, Dept Med, Providence, RI 02912 USA
关键词
HIV/AIDS; Castleman disease; lymphoma; Kaposi sarcoma; lymphoproliferative disorder; immune reconstitution inflammatory syndrome; Epstein-Barr virus; human herpesvirus 8; hepatitis C; C VIRUS-INFECTION; LYMPHOMA; RITUXIMAB; REMISSION; HHV-8;
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The case of a 45-year-old man with HIV disease with bulky lymphadenopathy, fevers, and weight loss is presented. Immune reconstitution inflammatory syndrome was initially believed to be the cause, but the patient was found to suffer from Kaposi sarcoma, multicentric Castleman disease, hemophagocytic syndrome, and a newly described lymphoproliferative disorder. The diagnostic reasoning related to the causes of the fulminant illness is discussed as well as the roles of Epstein-Barr virus, human herpesvirus 8, and hepatitis C virus in the patient's clinical presentation and the therapeutic choices.
引用
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页码:596 / +
页数:4
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