Multicentric Castleman disease, Kaposi sarcoma, hemophagocytic syndrome, and a novel HHV8-lymphoproliferative disorder

被引：0
|
作者：
Yates, Jennifer A. [1 ]
Zakai, Neil A. [2 ,3 ]
Griffith, Rogers C. [4 ]
Wing, Edward J. [5 ]
Schiffman, Fred J. [5 ]
机构：
[1] Johns Hopkins Univ Hosp, Dept Internal Med, Baltimore, MD 21287 USA
[2] Univ Vermont, Dept Med, Burlington, VT 05405 USA
[3] Fletcher Allen Hlth Care, Burlington, VT USA
[4] Brown Univ, Dept Pathol, Providence, RI 02912 USA
[5] Brown Univ, Dept Med, Providence, RI 02912 USA
来源：
AIDS READER | 2007年 / 17卷 / 12期
关键词：
HIV/AIDS; Castleman disease; lymphoma; Kaposi sarcoma; lymphoproliferative disorder; immune reconstitution inflammatory syndrome; Epstein-Barr virus; human herpesvirus 8; hepatitis C; C VIRUS-INFECTION; LYMPHOMA; RITUXIMAB; REMISSION; HHV-8;
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The case of a 45-year-old man with HIV disease with bulky lymphadenopathy, fevers, and weight loss is presented. Immune reconstitution inflammatory syndrome was initially believed to be the cause, but the patient was found to suffer from Kaposi sarcoma, multicentric Castleman disease, hemophagocytic syndrome, and a newly described lymphoproliferative disorder. The diagnostic reasoning related to the causes of the fulminant illness is discussed as well as the roles of Epstein-Barr virus, human herpesvirus 8, and hepatitis C virus in the patient's clinical presentation and the therapeutic choices.
引用
收藏
页码：596 / +
页数：4
相关论文
共 50 条
  • [21] Tocilizumab in patients with symptomatic Kaposi sarcoma herpesvirus-associated multicentric Castleman disease
    Ramaswami, Ramya
    Lurain, Kathryn
    Peer, Cody J.
    Serquina, Anna
    Wang, Victoria
    Widell, Anaida
    Goncalves, Priscila
    Steinberg, Seth M.
    Marshall, Vickie
    George, Jomy
    Figg, William D.
    Whitby, Denise
    Ziegelbauer, Joseph
    Uldrick, Thomas S.
    Yarchoan, Robert
    BLOOD, 2020, 135 (25) : 2316 - 2319
  • [22] HHV-8-Associated Multicentric Castleman Disease, a Diagnostic Challenge in a Patient With Acquired Immunodeficiency Syndrome and Fever
    Dunn, Robert
    Jariwal, Roopam
    Venter, Frederick
    Mishra, Shikha
    Bhandohal, Janpreet
    Cobos, Everado
    Heidari, Arash
    JOURNAL OF INVESTIGATIVE MEDICINE HIGH IMPACT CASE REPORTS, 2022, 10
  • [23] TWO HHV8-RELATED ILLNESSES IN A HIV-NEGATIVE PATIENT: KAPOSI'S SARCOMA AND MULTICENTRIC CASTLEMAN'S DISEASE. RESPONSE TO TREATMENT WITH RITUXIMAB AND CHOP
    Pastor, M. A.
    Vasco, B.
    Mosquera, J. M.
    Deben, G.
    Bautista, P.
    Requena, L.
    ACTAS DERMO-SIFILIOGRAFICAS, 2006, 97 (06): : 385 - 390
  • [24] Role of 18F-FDG PET/CT in the Management of Patients Affected by HHV-8-Associated Multicentric Castleman's Disease
    Albano, Domenico
    Bertagna, Francesco
    Cerudelli, Elisabetta
    Dondi, Francesco
    Giubbini, Raffaele
    HEMATO, 2021, 2 (02): : 383 - 391
  • [25] Durable remission of both multicentric Castleman's disease and Kaposi's sarcoma with valganciclovir, rituximab and liposomal doxorubicin in an HHV-8-positive, HIV-negative patient
    Murphy, C.
    Hawkes, E.
    Chionh, F.
    Chong, G.
    JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2017, 42 (01) : 111 - 114
  • [26] Autoimmune hypoglycemia expands the biological spectrum of HHV8+ multicentric Castleman disease
    Arnautou, Pierre
    Auclair, Martine
    Fellahi, Soraya
    Bouche, Clara
    Fieschi, Claire
    Barrak, Elias
    Queyrel-Moranne, Viviane
    Chaillous, Lucy
    Blin, Nicolas
    Malphettes, Marion
    Fadlallah, Jehane
    Bertinchamp, Remi
    Gerard, Laurence
    Bengoufa, Djaouida
    Galicier, Lionel
    Oksenhendler, Eric
    Vigouroux, Corinne
    Boutboul, David
    BLOOD ADVANCES, 2021, 5 (07) : 1848 - 1852
  • [27] Pathology of bone marrow in human herpes virus-8 (HHV8)-associated multicentric Castleman disease
    Bacon, CM
    Miller, RF
    Noursadeghi, M
    McNamara, C
    Du, MQ
    Dogan, A
    BRITISH JOURNAL OF HAEMATOLOGY, 2004, 127 (05) : 585 - 591
  • [28] Human herpesvirus 8 and associated diseases: Kaposi's sarcoma, body cavity based lymphoma and multicentric Castleman disease: clinical and molecular epidemiology
    Gessain, A
    BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE, 1997, 181 (06): : 1023 - 1034
  • [29] EBV+ HHV-8+Multicentric Castleman Disease With Plasmablastic Aggregates in an HIV plus Man: An Evolving Clinicopathologic Entity
    Shivane, Aditya
    Pearce, Amy
    Khatib, Nadia
    Smith, Mark E. F.
    INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY, 2018, 26 (04) : 338 - 341
  • [30] The role of Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) in lymphoproliferative diseases
    Cesarman, E
    Knowles, DM
    SEMINARS IN CANCER BIOLOGY, 1999, 9 (03) : 165 - 174
12345