Metagenomic applications in microbial diversity, bioremediation, pollution monitoring, enzyme and drug discovery. A review

被引:70
作者
Datta, Saptashwa [1 ]
Rajnish, K. Narayanan [1 ]
Samuel, Melvin S. [2 ]
Pugazlendhi, Arivalagan [3 ]
Selvarajan, Ethiraj [1 ]
机构
[1] SRM Inst Sci & Technol, Sch Bioengn, Dept Genet Engn, Chennai, Tamil Nadu, India
[2] Indian Inst Technol, Sch Environm Sci & Engn, Kharagpur 721302, W Bengal, India
[3] Ton Duc Thang Univ, Innovat Green Prod Synth & Renewable Environm Dev, Fac Environm & Labour Safety, Ho Chi Minh City, Vietnam
关键词
Metagenomics; Diagnostics; Enzymes; Environmental monitoring; Pathogen monitoring; ANTIBIOTIC-RESISTANCE GENES; FUNCTIONAL METAGENOMICS; BACTERIAL PATHOGENS; ALPHA-AMYLASE; TREATMENT PLANTS; GUT MICROBIOME; SOIL; IDENTIFICATION; REMOVAL; SALT;
D O I
10.1007/s10311-020-01010-z
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Metagenomics is a technology employed to study genetic material directly isolated from environmental samples. Metagenomics thus reveals knowledge on microbial communities of uncultivable organisms in environmental niches, using screening technologies based on sequence and function. Applications include the identification of novel bacteria or gene clusters encoding for enzymes that degrade pollutants. Metagenomics also help to diagnose and monitor pathogens. Here, we review application of metagenomics for bioremediation, pollution monitoring, enzyme, and drug discovery.
引用
收藏
页码:1229 / 1241
页数:13
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