Two reaction modes of 1-sulfonyl-1,2,3-triazoles and pyridinium 1,4-zwitterionic thiolates: catalyst-free synthesis of pyrido[1,2-a]pyrazine derivatives and 1,4-thiazine derivatives

被引：19

作者：

Duan, Shengguo ^{[1
]}

Chen, Cong ^{[1
]}

Chen, Yidian ^{[1
]}

Jie, Yuchen ^{[1
]}

Luo, Huan ^{[1
]}

Xu, Ze-Feng ^{[1
]}

Cheng, Bin ^{[2
]}

Li, Chuan-Ying ^{[1
]}

机构：

[1] Zhejiang Sci Tech Univ, Dept Chem, Key Lab Surface & Interface Sci Polymer Mat Zheji, Hangzhou 310018, Peoples R China

[2] Shenzhen Polytech, Inst Marine Biomed, Shenzhen 518055, Peoples R China

来源：

ORGANIC CHEMISTRY FRONTIERS | 2021年 / 8卷 / 24期

基金：

中国国家自然科学基金;

关键词：

HETEROCYCLES; TRANSANNULATION; 1,2,3-TRIAZOLES; REARRANGEMENT; INDOLIZINES; TRIAZOLES;

D O I：

10.1039/d1qo01237a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two reaction modes of 1-sulfonyl-1,2,3-triazoles and pyridinium 1,4-zwitterionic thiolates were described. Pyrido[1,2-a]pyrazine derivatives were obtained in moderate yields when 4-OEt substituted triazoles were employed in reactions, and 1,4-thiazine derivatives were synthesized when 4-NPhth substituted triazoles were employed. The mechanism may involve a sulfur migration via an addition/elimination process which has never been reported in the previous pyridinium 1,4-zwitterionic thiolate related works.

引用

页码：6962 / 6967

页数：6

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