GPDE: A biological proteomic database for biomarker discovery and evaluation

被引：12
作者：
Griss, Johannes [1 ]
Haudek-Prinz, Verena [1 ]
Gerner, Christopher [1 ]
机构：
[1] Med Univ Vienna, Ctr Comprehens Canc, Dept Med 1, A-1090 Vienna, Austria
来源：
PROTEOMICS | 2011年 / 11卷 / 05期
关键词：
Bioinformatics; Biomarker discovery; Database; PRoteomics IDEntifications database; CELLS; PROFILES;
D O I：
10.1002/pmic.201000507
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Clinical proteomics faces extremely complex and variable data. Here, we present an updated version of the Griss Proteomics Database Engine (GPDE): A free biological proteomic database specifically designed for clinical proteomics and biomarker discovery (http://gpde.sourceforge.net). It combines experiments based on investigated cell types thereby supporting customizable biological meta-analyses. Through the new features described here, the GPDE now became a powerful yet easy-to-use tool to support the fast identification and reliable evaluation of biomarker candidates.
引用
收藏
页码：1000 / 1004
页数：5
相关论文
共 16 条
  • [1] [Anonymous], NUCL ACIDS RES
  • [2] An ontology for cell types
    Bard, J
    Rhee, SY
    Ashburner, M
    [J]. GENOME BIOLOGY, 2005, 6 (02)
  • [3] PRIDE Converter: making proteomics data-sharing easy
    Barsnes, Harald
    Vizcaino, Juan Antonio
    Eidhammer, Ingvar
    Martens, Lennart
    [J]. NATURE BIOTECHNOLOGY, 2009, 27 (07) : 598 - 599
  • [4] PeptideAtlas: a resource for target selection for emerging targeted proteomics workflows
    Deutsch, Eric W.
    Lam, Henry
    Aebersold, Ruedi
    [J]. EMBO REPORTS, 2008, 9 (05) : 429 - 434
  • [5] GRISS J, 2009, J PROTEOM BIOINFORM, V2, P167, DOI DOI 10.4172/JPB.1000074
  • [6] Cytoplasmic Proteome and Secretome Profiles of Differently Stimulated Human Dendritic Cells
    Gundacker, Nina C.
    Haudek, Verena J.
    Wimmer, Helge
    Slany, Astrid
    Griss, Johannes
    Bochkov, Valery
    Zielinski, Christoph
    Wagner, Oswald
    Stoeckl, Johannes
    Gerner, Christopher
    [J]. JOURNAL OF PROTEOME RESEARCH, 2009, 8 (06) : 2799 - 2811
  • [7] Li Xuanwen, 2009, Archives of Physiology and Biochemistry, V115, P311, DOI 10.3109/13813450903390039
  • [8] MOHIEN CU, 2010, PROTEOMICS
  • [9] Entering a New Era of Rational Biomarker Discovery for Early Detection of Melanoma Metastases: Secretome Analysis of Associated Stroma Cells
    Paulitschke, Verena
    Kunstfeld, Rainer
    Mohr, Thomas
    Slany, Astrid
    Micksche, Michael
    Drach, Johannes
    Zielinski, Christoph
    Pehamberger, Hubert
    Gerner, Christopher
    [J]. JOURNAL OF PROTEOME RESEARCH, 2009, 8 (05) : 2501 - 2510
  • [10] Scaffold: A bioinformatic tool for validating MS/MS-based proteomic studies
    Searle, Brian C.
    [J]. PROTEOMICS, 2010, 10 (06) : 1265 - 1269
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