Multicentric Castleman's disease associated with inherited epidermolysis bullosa

被引：3

作者：

Kawakami, Y

Nishibu, A

Kikuchi, S

Ohtsuka, M

Nakamura, K

Nozawa, Y

Abe, M

Iwatsuki, K

Kaneko, F

机构：

[1] Fukushima Med Univ, Sch Med, Dept Dermatol, Fukushima 9601295, Japan

[2] Fukushima Med Univ, Sch Med, Dept Pathol 1, Fukushima 9601295, Japan

[3] Okayama Univ, Grad Sch Med & Dent, Dept Dermatol, Okayama 7008530, Japan

来源：

JOURNAL OF DERMATOLOGY | 2003年 / 30卷 / 09期

关键词：

interleukin-6; hypergammaglobulinemia; dystrophic epidermolysis bullosa;

D O I：

10.1111/j.1346-8138.2003.tb00459.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Multicentric Castleman's disease (MCD) is a rare disorder characterized by fever, polyclonal hypergammaglobulinemia, and generalized lymphadenopathy. It has three histological characteristics: a recognizable architecture, germinal center abnormalities, and plasmacytosis. Inherited epidermolysis bullosa (EB) is also a rare disorder caused by a genetic defect. We report a 43-year-old patient with dystrophic EB, non-Hallopeau-Siemens recessive type or dominant type, displaying clinicopathologic features of MCD. In addition, his serum interleukin-6, which is thought to be responsible for the clinical symptoms in MCD, was elevated.

引用

页码：689 / 693

页数：5

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