Transcranial Direct Current Stimulation for Poststroke Motor Recovery: Challenges and Opportunities

被引：30
作者：
Feng, Wuwei [1 ,2 ]
Kautz, Steven A. [2 ,3 ]
Schlaug, Gottfried [4 ]
Meinzer, Caitlyn [5 ]
George, Mark S. [6 ]
Chhatbar, Pratik Y. [1 ]
机构：
[1] Med Univ South Carolina, Dept Neurol, 96 Jonathan Lucas St, Charleston, SC 29425 USA
[2] Med Univ South Carolina, Dept Hlth Sci & Res, Charleston, SC 29425 USA
[3] Ralph H Johnson VA Med Ctr, Charleston, SC USA
[4] Harvard Med Sch, Dept Neurol, Neuroimaging & Stroke Recovery Lab, Beth Israel Deaconess Med Ctr, Boston, MA USA
[5] Med Univ South Carolina, Dept Publ Hlth Sci, Charleston, SC 29425 USA
[6] Med Univ South Carolina, Dept Psychiat & Behav Sci, Charleston, SC 29425 USA
来源：
PM&R | 2018年 / 10卷 / 09期
基金：
美国国家卫生研究院;
关键词：
INTERHEMISPHERIC INHIBITION; ELECTRICAL-STIMULATION; STROKE REHABILITATION; WHITE-MATTER; CORTEX; TDCS; EXCITABILITY; THERAPY; MULTICENTER; MODULATION;
D O I：
10.1016/j.pmrj.2018.04.012
中图分类号：
R49 [康复医学];
学科分类号：
100215 ;
摘要：
There has been a renewed research interest in transcranial direct current stimulation (tDCS) as an adjunctive tool for post-stroke motor recovery as it has a neuro-modulatory effect on the human cortex. However, there are barriers towards its successful application in motor recovery as several scientific issues remain unresolved, including device-related issues (ie, dose-response relationship, safety and tolerability concerns, interhemispheric imbalance model, and choice of montage) and clinical trial related issues (ie, patient selection, timing of study, and choice of outcomes). This narrative review examines and discusses the existing challenges in using tDCS as a brain modulation tool in facilitating recovery after stroke. Potential solutions pertinent to using tDCS with the goal of harnessing the brains plasticity are proposed.
引用
收藏
页码：S157 / S164
页数：8
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