Transpupillary thermotherapy for choroidal metastases

Introduction:We report on a case with bilateral choroidal metastases derived from a renal cell carcinoma 13 years after nephrectomy. The treatment modality is discussed. Methods: A male patient (58 years of age) presented with asymptomatic bilateral choroidal metastases deriving from renal cell carcinoma. The right kidney had been removed because of renal cell carcinoma 13 years before the appearance of the choroidal metastases, He had full visual acuity (20/20) and normal intraocular pressure in both eyes. Fundus examination showed a small tumor in the peripheral choroidea of his right eye and an intermediate-sized solid tumor in the periphery of his left eye. Results: The tumor of the right eye was treated by TTT and the tumor of the left eye by Ru-106 plaque radiotherapy. The tumors showed total regression into flat chorioretinal atrophies in both eyes and no tumor could be found 13 moths after treatment maintaining full visual acuity (20/20), Conclusion: Asymptomatic ocular metastases can develop even many years after removal of the primary tumor, TTT and Ru-106 brachytherapy are useful treatment modalities in cases of small and intermediate-sized choroidal metastases, Copyright (C) 2001 S. Karger AG, Basel.