Recent advances in the treatment of acromegaly

被引：3

作者：

Aghi, Manish ^{[1
]}

Blevins, Lewis S., Jr. ^{[1
]}

机构：

[1] Univ Calif San Francisco, Dept Neurol Surg, Calif Ctr Pituitary Disorders, San Francisco, CA 94143 USA

来源：

CURRENT OPINION IN ENDOCRINOLOGY DIABETES AND OBESITY | 2009年 / 16卷 / 04期

关键词：

acromegaly; growth hormone receptor antagonist; lanreotide; octreotide; pegvisomant; radiosurgery; somatostatin receptor analogs; transphenoidal surgery; FOLLOW-UP; RADIOSURGERY; PEGVISOMANT;

D O I：

10.1097/MED.0b013e32832d88e4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Purpose of review Description of recent outcomes and approaches to the treatment of patients with de-novo and recurrent acromegaly. Recent findings Radiosurgery for acromegaly results in a higher likelihood of remission and an earlier time to remission than does conventional radiotherapy. Somatostatin analogs results in control of acromegaly and one half of patients. Combining treatment with pegvisomant and somatostatin analogs results in overall improved quality of life. Summary Existing treatments offer patients and their treating physicians opportunities to restore life expectancy to normal and reverse many of the symptoms and signs of acromegaly.

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页码：304 / 307

页数：4

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