Recent advances in the treatment of acromegaly

被引:3
|
作者
Aghi, Manish [1 ]
Blevins, Lewis S., Jr. [1 ]
机构
[1] Univ Calif San Francisco, Dept Neurol Surg, Calif Ctr Pituitary Disorders, San Francisco, CA 94143 USA
关键词
acromegaly; growth hormone receptor antagonist; lanreotide; octreotide; pegvisomant; radiosurgery; somatostatin receptor analogs; transphenoidal surgery; FOLLOW-UP; RADIOSURGERY; PEGVISOMANT;
D O I
10.1097/MED.0b013e32832d88e4
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose of review Description of recent outcomes and approaches to the treatment of patients with de-novo and recurrent acromegaly. Recent findings Radiosurgery for acromegaly results in a higher likelihood of remission and an earlier time to remission than does conventional radiotherapy. Somatostatin analogs results in control of acromegaly and one half of patients. Combining treatment with pegvisomant and somatostatin analogs results in overall improved quality of life. Summary Existing treatments offer patients and their treating physicians opportunities to restore life expectancy to normal and reverse many of the symptoms and signs of acromegaly.
引用
收藏
页码:304 / 307
页数:4
相关论文
共 50 条
  • [1] RECENT ADVANCES IN PATHOGENESIS, DIAGNOSIS, AND MANAGEMENT OF ACROMEGALY
    MELMED, S
    HO, K
    KLIBANSKI, A
    REICHLIN, S
    THORNER, M
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1995, 80 (12): : 3395 - 3402
  • [2] RECENT DEVELOPMENTS IN THE TREATMENT OF ACROMEGALY
    LUDECKE, DK
    NEUROSURGICAL REVIEW, 1985, 8 (3-4) : 167 - 173
  • [3] RECENT TRENDS IN TREATMENT OF ACROMEGALY
    HAMLIN, H
    ACTA NEUROCHIRURGICA, 1973, 29 (3-4) : 261 - 262
  • [4] ADVANCES IN THE NEUROSURGICAL AND COMBINED TREATMENT OF PATIENTS WITH ACROMEGALY
    Ibrahim, Sameh R. A.
    Shkarubo, Alexey
    Astafyeva, Ludmila
    Chmutin, Gennady
    Chmutin, Egor
    ARCHIV EUROMEDICA, 2021, 11 (04): : 104 - 107
  • [5] The changing face of acromegaly—advances in diagnosis and treatment
    Antônio Ribeiro-Oliveira Jr
    Ariel Barkan
    Nature Reviews Endocrinology, 2012, 8 : 605 - 611
  • [6] The changing face of acromegaly-advances in diagnosis and treatment
    Ribeiro-Oliveira, Antonio, Jr.
    Barkan, Ariel
    NATURE REVIEWS ENDOCRINOLOGY, 2012, 8 (10) : 605 - 611
  • [7] RECENT ADVANCES IN THE TREATMENT OF POLIOMYELITIS
    AFFELDT, JE
    JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1954, 156 (01): : 12 - 15
  • [8] Recent advances in the treatment of oligodendrogliomas
    Mark Agulnik
    Warren P. Mason
    Current Neurology and Neuroscience Reports, 2006, 6 : 212 - 217
  • [9] RECENT ADVANCES IN THE TREATMENT OF MEGACOLON
    BARGEN, JA
    MEDICAL CLINICS OF NORTH AMERICA, 1948, (NMAYO) : 981 - 987
  • [10] RECENT ADVANCES IN THE TREATMENT OF ASCITES
    RODES, J
    CURRENT OPINION IN GASTROENTEROLOGY, 1987, 3 (04) : 550 - 555