Muscle degeneration in chicks caused by Senna occidentalis seeds

被引：14
作者：
Haraguchi, M
Górniak, SL
Calore, EE
Cavaliere, MJ
Raspantini, PC
Calore, NMP
Dagli, MLZ
机构：
[1] Biol Inst Sao Paulo, Div Anim Biol, Pharmacol Sect, BR-04014002 Sao Paulo, Brazil
[2] Univ Sao Paulo, Res Ctr Vet Toxicol, CEPTOX, BR-05508 Sao Paulo, Brazil
[3] Univ Sao Paulo, Fac Vet Med & Zootechny, Emilio Ribas Inst, Sect Pathol, Sao Paulo, Brazil
[4] Univ Sao Paulo, Fac Vet Med & Zootechny, Adolfo Lutz Inst,Lab Mol Pathol, Sect Pathol, Sao Paulo, Brazil
[5] Univ Sao Paulo, Fac Vet Med & Zootechny, Dept Pathol, Sao Paulo, Brazil
来源：
AVIAN PATHOLOGY | 1998年 / 27卷 / 04期
基金：
巴西圣保罗研究基金会;
关键词：
D O I：
10.1080/03079459808419350
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
Acute intoxication with Senna occidentalis seeds was studied in chicks. Seven-day-old chicks were fed ground dried seeds of this plant mixed with regular chicken ration at a concentration of 4% by weight for 15 days. Feed intake and body weight were markedly affected and a high level of lethality was observed. Necropsy examination of chicks from the experimental group revealed paleness and atrophy of thoracic muscles. Degenerative and necrotic fibres were observed in skeletal muscle by histological examination. Muscle histochemistry showed accumulation of lipids and numerous acid phosphatase-positive muscle fibres. Electron microscopy revealed atrophic muscle fibres, lipid storage, dilatation of the sarcoplasmic reticulum and abnormal mitochondria.
引用
收藏
页码：346 / 351
页数：6
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