Synthesis and reactions of 6(4)-(P-benzylphenyl)-4(6)-phenylpyrimidine-2(1H) thione

被引：0

作者：

Wasfy, AAF

Amine, MS

Eissa, AMF

机构：

来源：

HETEROCYCLIC COMMUNICATIONS | 1996年 / 2卷 / 04期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1,3-Diaryl-2-Propen-1-one reacted with thiourea in the presence of sodium ethoxide to furnish 4,6-diarylpyrimidine-2(1H) thione (2) under bar. The behaviour of (2) under bar towards nitrogen nucleophiles, and carbon electrophiles under Michael reaction conditions have been investigated. The oxidation of the thione (2) under bar gave the corresponding disulphide derivative <(12)under bar>. Acylation of (2) under bar yielded the corresponding S-acetyl-<(13)under bar> and N-benzoyl-<(14)under bar> derivatives, respectively.

引用

页码：375 / 381

页数：7

共 13 条

[1] REACTION OF ALPHA,BETA-UNSATURATED KETONES WITH GUANIDINE - SUBSTITUENT EFFECTS ON THE PROTONATION CONSTANTS OF 2-AMINO-4,6-DIARYLPYRIMIDINES
ALHAJJAR, FH
SABRI, SS
[J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 1982, 19 (05) : 1087 - 1092
[2] ACETYLENIC KETONES .5. REACTION OF ACETYLENIC KETONES WITH THIOUREA AND SOME OF ITS DERIVATIVES
BADDAR, FG
ALHAJJAR, FH
ELRAYYES, NR
[J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 1978, 15 (01) : 105 - 112
[3] CHEN O, 1988, CHEM ABSTR 186698, V108
[4] ELHASHASH MA, 1991, CHINESE J CHEM, V1, P78
[5] ESSAWY SA, 1991, EGYPT J CHEM, V34, P271
[6] GHONEIM KM, 1986, J INDIAN CHEM SOC, V53, P914
[7] SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF 1-(2,4-DICHLOROBENZOYL)-4-SUBSTITUTED THIOSEMICARBAZIDES, 1,2,4-TRIAZOLES AND THEIR METHYL-DERIVATIVES
GOSWAMI, BN
KATAKY, JCS
BARUAH, JN
[J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 1984, 21 (04) : 1225 - 1229
[8] KREUTZBERGER A, 1984, CHEM ABSTR 211094, V101
[9] OZAKI S, 1984, CHEM ABSTR, V101, P55035
[10] RECTOR DL, 1988, CHEM ABSTR 167292, V108

← 1 2 →