Vitamin-E diffused highly cross-linked polyethylene liner compared to standard liners in total hip arthroplasty. A randomized, controlled trial

被引:49
作者
Salemyr, Mats [1 ]
Muren, Olle [1 ]
Ahl, Torbjorn [1 ]
Boden, Henrik [1 ]
Chammout, Ghazi [1 ]
Stark, Andre [1 ]
Skoldenberg, Olof [1 ]
机构
[1] Karolinska Inst, Danderyd Hosp, Dept Clin Sci, Div Orthopaed, Stockholm, Sweden
关键词
Total hip arthroplasty; Vitamin-E; Osteoarthritis; Polyethylene; Radiostereometry; Head penetration; Wear; WEAR; PCA; RSA;
D O I
10.1007/s00264-015-2680-3
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Purpose We hypothesized that a vitamin E-treated polyethylene articulating liner had lower femoral head penetration than a conventional liner. Methods Fifty-one patients with primary hip osteoarthritis were randomized to an uncemented cup with either vitamin E-treated highly cross-linked polyethylene (HXLPE) (vitamin-e group, n = 25) or a standard HXLPE liner (control group, n = 26) and followed for two years after surgery. The outcome variable was polyethylene (PE) linear head penetration, measured with radiostereometry (RSA). Results The head penetration in x- (medial/lateral) and y- (vertical) axes was significantly lower for the vitamin E-treated liner up to two years with a mean difference between the groups of 0.10 mm (95 % CI 0.04-0.18) and 0.08 mm (95 % CI 0.01-0.15), respectively. The initial total penetration was lower for the vitamin-E group but did not reach statistical significance at two years with a mean difference between the groups of 0.07 mm (95 % CI -0.001 to 0.15, p = 0.09). We found no differences in clinical outcome between the groups. Conclusions In this prospective, randomized, controlled trial on a new vitamin-E diffused HXLPE liner we found, compared to a conventional HXLPE liner, lower initial head penetration and lower superior and medial wear. A longer follow-up than two years is necessary to demonstrate lower overall head penetration in vitamin-E liners compared to contemporary highly cross-linked PE.
引用
收藏
页码:1499 / 1505
页数:7
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