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Vitamin-E diffused highly cross-linked polyethylene liner compared to standard liners in total hip arthroplasty. A randomized, controlled trial
被引:49
作者:
Salemyr, Mats
[1
]
Muren, Olle
[1
]
Ahl, Torbjorn
[1
]
Boden, Henrik
[1
]
Chammout, Ghazi
[1
]
Stark, Andre
[1
]
Skoldenberg, Olof
[1
]
机构:
[1] Karolinska Inst, Danderyd Hosp, Dept Clin Sci, Div Orthopaed, Stockholm, Sweden
关键词:
Total hip arthroplasty;
Vitamin-E;
Osteoarthritis;
Polyethylene;
Radiostereometry;
Head penetration;
Wear;
WEAR;
PCA;
RSA;
D O I:
10.1007/s00264-015-2680-3
中图分类号:
R826.8 [整形外科学];
R782.2 [口腔颌面部整形外科学];
R726.2 [小儿整形外科学];
R62 [整形外科学(修复外科学)];
学科分类号:
摘要:
Purpose We hypothesized that a vitamin E-treated polyethylene articulating liner had lower femoral head penetration than a conventional liner. Methods Fifty-one patients with primary hip osteoarthritis were randomized to an uncemented cup with either vitamin E-treated highly cross-linked polyethylene (HXLPE) (vitamin-e group, n = 25) or a standard HXLPE liner (control group, n = 26) and followed for two years after surgery. The outcome variable was polyethylene (PE) linear head penetration, measured with radiostereometry (RSA). Results The head penetration in x- (medial/lateral) and y- (vertical) axes was significantly lower for the vitamin E-treated liner up to two years with a mean difference between the groups of 0.10 mm (95 % CI 0.04-0.18) and 0.08 mm (95 % CI 0.01-0.15), respectively. The initial total penetration was lower for the vitamin-E group but did not reach statistical significance at two years with a mean difference between the groups of 0.07 mm (95 % CI -0.001 to 0.15, p = 0.09). We found no differences in clinical outcome between the groups. Conclusions In this prospective, randomized, controlled trial on a new vitamin-E diffused HXLPE liner we found, compared to a conventional HXLPE liner, lower initial head penetration and lower superior and medial wear. A longer follow-up than two years is necessary to demonstrate lower overall head penetration in vitamin-E liners compared to contemporary highly cross-linked PE.
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页码:1499 / 1505
页数:7
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