Expression of Soluble Endoglin and sFlt-1 in Peripheral Blood of Preeclampsia

被引：0

作者：

Fan, Minghua ^{[1
]}

Xu, Yongping ^{[1
]}

Qiu, Jianqing ^{[1
]}

机构：

[1] Shandong Univ, Dept Obstet & Gynecol, Hosp 2, Jinan, Peoples R China

来源：

2016 3RD INTERNATIONAL SYMPOSIUM ON ENGINEERING TECHNOLOGY, EDUCATION AND MANAGEMENT (ISETEM 2016) | 2016年

关键词：

Preeclampsia; Soluble endoglin; Soluble fms-like tyrosine kinase receptor 1; Angiogenic factor;

D O I：

暂无

中图分类号：

G40 [教育学];

学科分类号：

040101 ; 120403 ;

摘要：

Objective To investigate the expression and significance of serum soluble endoglin (sEng) and soluble fms-like tyrosine kinase 1 (sFlt-1) in preeclampsia. Methods Serum levels of sEng 1 and sFlt-1 were determined by enzyme linked immunosorbent assay. Results The serum level of sEng of the preeclampsia group (6.39 +/- 2.15) ng/ml was significantly higher than that of the control (2.16 +/- 0.31) ng/ml, P<0.01, especially of early-onset severe preeclampsia. The serum level of sFlt-1 of the preeclampsia group (411.11 +/- 80.19) pg/ml was significantly higher than that of the third trimester group (27.57 +/- 4.36) pg/ml, but sFlt-1 did not correlate with the most severe forms of the disease. Conclusion Serum levels of sEng and sFlt-1 are significantly increased in preeclampsia, and the serum level of sEng is even higher in severe preeclampsia patients.

引用

页码：112 / 116

页数：5